Function and Biology Details
Reactions catalysed:
ATP + 1-phosphatidyl-1D-myo-inositol 3-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- Phosphatidylinositol-4-phosphate 4/5-kinase, core
- GroEL-like apical domain superfamily
- 1-phosphatidylinositol-3phosphate-5-kinase
- 1-phosphatidylinositol-3-phosphate 5-kinase, PIPK catalytic domain
- Phosphatidylinositol-4-phosphate 5-kinase, N-terminal
- TCP-1-like chaperonin intermediate domain superfamily
- Chaperonin Cpn60/GroEL/TCP-1 family
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
1-phosphatidylinositol 3-phosphate 5-kinase (preferred)
PDBe Complex ID:
PDB-CPX-195138 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
1-phosphatidylinositol 3-phosphate 5-kinase
Molecule details ›
Chain: P
Length: 264 amino acids
Theoretical weight: 30.46 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Phosphatidylinositol-4-phosphate 5-Kinase
Length: 264 amino acids
Theoretical weight: 30.46 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
Q9Y2I7 (Residues: 1822-2085; Coverage: 13%)
Sequence domains: Phosphatidylinositol-4-phosphate 5-Kinase
1-phosphatidylinositol 3-phosphate 5-kinase
Molecule details ›
Chain: A
Length: 453 amino acids
Theoretical weight: 51.41 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: TCP-1/cpn60 chaperonin family
Length: 453 amino acids
Theoretical weight: 51.41 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: Q9Y2I7 (Residues: 547-983; Coverage: 21%)
Sequence domains: TCP-1/cpn60 chaperonin family
