› 7kc6

X-ray diffraction
1.85Å resolution

X-ray structure of Lfa-1 I domain in complex with Lovastatin collected at 273 K

Released:
DOI: 10.2210/pdb7kc6/pdb
PDB entry 7kc6 coloured by chain, front view.
PDB entry 7kc6 coloured by chain, side view.
PDB entry 7kc6 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Woldeyes RA, Hallenbeck KK, Pfaff SJ, Lee G, Cortez SV, Kelly MJ, Akassoglou K, Arkin MR, Fraser JS

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149031 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Integrin alpha-L Chains: A, C
Molecule details ›
Chains: A, C
Length: 184 amino acids
Theoretical weight: 20.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: P20701 (Residues: 153-334; Coverage: 16%)
Gene names: CD11A, ITGAL
Sequence domains: von Willebrand factor type A domain

Ligands and Environments

2 bound ligands:
Ligand 803 2 x 803
Ligand MG 2 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Unit cell:
a: 66.889Å b: 46.078Å c: 127.233Å
α: 90° β: 104.606° γ: 90°
R-values:
R R work R free
0.176 0.173 0.225
Expression system: Escherichia coli K-12

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