Function and Biology Details
Reaction catalysed:
Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
Ricin A chain and IG-heavy chain (preferred)
PDBe Complex ID:
PDB-CPX-208793 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (6 distinct):
Ricin A chain
Molecule details ›
Chains: A, D
Length: 267 amino acids
Theoretical weight: 29.94 KDa
Source organism: Ricinus communis
UniProt:
Length: 267 amino acids
Theoretical weight: 29.94 KDa
Source organism: Ricinus communis
UniProt:
- Canonical:
P02879 (Residues: 36-302; Coverage: 49%)
Ricin B chain
Molecule details ›
Chains: B, E
Length: 262 amino acids
Theoretical weight: 28.99 KDa
Source organism: Ricinus communis
UniProt:
Length: 262 amino acids
Theoretical weight: 28.99 KDa
Source organism: Ricinus communis
UniProt:
- Canonical: P02879 (Residues: 315-576; Coverage: 48%)
Ligands and Environments
Experiments and Validation Details
X-ray source:
RIGAKU MICROMAX-007 HF
Spacegroup:
P1
Expression system: Escherichia coli
