› 7kei

X-ray diffraction
1.75Å resolution

DQA1*01:02/DQB1*06:02 in complex with a hemagglutinin peptide from the H1N1 pandemic flu virus.

Released:
DOI: 10.2210/pdb7kei/pdb
PDB entry 7kei coloured by chain, front view.
PDB entry 7kei coloured by chain, side view.
PDB entry 7kei coloured by chain, top view.
Source organisms:
Entry authors: Birtley JR, Stern LJ, Mellins ED, Jiang W

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-168355 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (5 distinct):
Ig-like domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 206 amino acids
Theoretical weight: 23.11 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: Q30066 (Residues: 1-195; Coverage: 86%)
Gene name: HLA-DQA1
Sequence domains:
Ig-like domain-containing protein Chain: B
Molecule details ›
Chain: B
Length: 210 amino acids
Theoretical weight: 24.08 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: Q5SU54 (Residues: 35-230; Coverage: 82%)
Gene name: HLA-DQB1
Sequence domains:
HA peptide from 2009 H1N1 pandemic flu virus. Chain: C
Molecule details ›
Chain: C
Length: 25 amino acids
Theoretical weight: 2.36 KDa
Source organism: H1N1 subtype
Expression system: Drosophila melanogaster

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, FUC
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
1 bound ligand:
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P21
Unit cell:
a: 59.31Å b: 58.255Å c: 67.507Å
α: 90° β: 96.08° γ: 90°
R-values:
R R work R free
0.205 0.203 0.233
Expression system: Drosophila melanogaster

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