7khd

X-ray diffraction
2.96Å resolution

Human GITR-GITRL complex

Released:
Model geometry
Fit model/data

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-193994 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Tumor necrosis factor ligand superfamily member 18 Chains: A, B
Molecule details ›
Chains: A, B
Length: 128 amino acids
Theoretical weight: 14.52 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9UNG2 (Residues: 50-177; Coverage: 72%)
Gene names: AITRL, GITRL, TL6, TNFSF18, UNQ149/PRO175
Tumor necrosis factor receptor superfamily member 18 Chains: C, D
Molecule details ›
Chains: C, D
Length: 137 amino acids
Theoretical weight: 14.65 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9Y5U5 (Residues: 26-162; Coverage: 63%)
Gene names: AITR, GITR, TNFRSF18, UNQ319/PRO364

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 17-ID
Spacegroup: I23
Unit cell:
a: 168.42Å b: 168.42Å c: 168.42Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.22 0.218 0.254
Expression system: Homo sapiens