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› 7kog

Electron Microscopy
4.25Å resolution

Lethocerus Myosin II complete coiled-coil domain resolved in its native environment

Released:
DOI: 10.2210/pdb7kog/pdb
PDB entry 7kog coloured by chain, front view.
PDB entry 7kog coloured by chain, side view.
PDB entry 7kog coloured by chain, top view.
Source organism: Lethocerus indicus
Primary publication:
The myosin II coiled-coil domain atomic structure in its native environment.
Rahmani H, Ma W, Hu Z, Daneshparvar N, Taylor DW, McCammon JA, Irving TC, Edwards RJ, Taylor KA
Proc Natl Acad Sci U S A 118 (2021)
PMID: 33782130
Related structures: EMD-22975

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-103943 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myosin heavy chain isoform Mhc_X1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 1971 amino acids
Theoretical weight: 225.23 KDa
Source organism: Lethocerus indicus
UniProt:
  • Canonical: A0A221IRH5 (Residues: 1-1971; Coverage: 100%)
Gene name: Mhc
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 4.25Å
Relevant EMDB volumes: EMD-22975

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Citations

5 review citations

Reassessing the unifying hypothesis for hypercontractility caused by myosin mutations in hypertrophic cardiomyopathy.
Spudich et al. (2024)
4 more

3 mentions without citation

Protein-protein interfaces in molecular glue-induced ternary complexes: classification, characterization, and prediction.
Rui et al. (2023)
2 more