7kyl

X-ray diffraction
2Å resolution

Powassan virus Envelope protein DIII in complex with neutralizing Fab POWV-80

Released:
Model geometry
Fit model/data

Function and Biology Details

Reactions catalysed:
Selective hydrolysis of -Xaa-Xaa-|-Yaa- bonds in which each of the Xaa can be either Arg or Lys and Yaa can be either Ser or Ala.
NTP + H(2)O = NDP + phosphate
ATP + H(2)O = ADP + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-207831 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
POWV-80 Fab heavy chain Chains: H, X
Molecule details ›
Chains: H, X
Length: 228 amino acids
Theoretical weight: 24.81 KDa
Source organism: Mus musculus
POWV-80 Fab light chain Chains: L, Y
Molecule details ›
Chains: L, Y
Length: 213 amino acids
Theoretical weight: 23.29 KDa
Source organism: Mus musculus
Envelope protein domain III Chains: E, Z

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: P21
Unit cell:
a: 79.154Å b: 62.557Å c: 141.546Å
α: 90° β: 97.97° γ: 90°
R-values:
R R work R free
0.191 0.19 0.224
Expression system: Escherichia coli