› 7kzf

Electron Microscopy
3.1Å resolution

High resolution cryo EM analysis of HPV16 identifies minor structural protein L2 and describes capsid flexibility

Released:
DOI: 10.2210/pdb7kzf/pdb
PDB entry 7kzf coloured by chain, front view.
PDB entry 7kzf coloured by chain, side view.
PDB entry 7kzf coloured by chain, top view.
Source organism: Human papillomavirus type 16
Primary publication:
High resolution cryo EM analysis of HPV16 identifies minor structural protein L2 and describes capsid flexibility.
Goetschius DJ, Hartmann SR, Subramanian S, Bator CM, Christensen ND, Hafenstein SL
Sci Rep 11 3498 (2021)
PMID: 33568731
Related structures: EMD-23081

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo 360-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136571 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Major capsid protein L1 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 503 amino acids
Theoretical weight: 56.1 KDa
Source organism: Human papillomavirus type 16
Expression system: Homo sapiens
UniProt:
  • Canonical: P03101 (Residues: 1-503; Coverage: 100%)
Gene name: L1
Sequence domains: L1 (late) protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.1Å
Relevant EMDB volumes: EMD-23081
Expression system: Homo sapiens

Quick links

Citations

3 review citations

New Perspectives in Therapeutic Vaccines for HPV: A Critical Review.
Gardella et al. (2022)
2 more

3 mentions without citation

Critical Residues Involved in the Coassembly of L1 and L2 Capsid Proteins of Human Papillomavirus 16.
Chen et al. (2023)
2 more