› 7l52

X-ray diffraction
1.85Å resolution

Crystal Structure of the Metallo Beta Lactamase L1 from Stenotrophomonas maltophilia Determined by Serial Crystallography

Released:
DOI: 10.2210/pdb7l52/pdb
Model geometry
Fit model/data
PDB entry 7l52 coloured by chain, front view.
PDB entry 7l52 coloured by chain, side view.
PDB entry 7l52 coloured by chain, top view.
Source organism: Stenotrophomonas maltophilia K279a
Entry authors: Wilamowski M, Kim Y, Sherrell DA, Lavens A, Maltseva N, Endres M, Babnigg G, Joachimiak A, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Reaction catalysed: 
a beta-lactam + H2O = a substituted beta-amino acid.
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-109537 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
beta-lactamase Chain: A
Molecule details ›
Chain: A
Length: 275 amino acids
Theoretical weight: 29.24 KDa
Source organism: Stenotrophomonas maltophilia K279a
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: B2FTM1 (Residues: 19-290; Coverage: 100%)
Gene name: Smlt2667
Sequence domains: Metallo-beta-lactamase superfamily

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P6422
Unit cell:
a: 105.668Å b: 105.668Å c: 99.332Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.177 0.175 0.217
Expression system: Escherichia coli BL21(DE3)

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