› 7l79

X-ray diffraction
2.83Å resolution

Crystal structure of broadly HIV-1-neutralizing antibody VRC40.01

Released:
DOI: 10.2210/pdb7l79/pdb
PDB entry 7l79 coloured by chain, front view.
PDB entry 7l79 coloured by chain, side view.
PDB entry 7l79 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of broadly HIV-1-neutralizing antibody
Zhou T
Cell Rep (2021)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-214376 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Heavy chain of VRC40.01 Chains: A, H
Molecule details ›
Chains: A, H
Length: 230 amino acids
Theoretical weight: 24.66 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Light chain of VRC40.01 Chains: B, L
Molecule details ›
Chains: B, L
Length: 214 amino acids
Theoretical weight: 23.62 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

1 bound ligand:
Ligand ZN 9 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P212121
Unit cell:
a: 62.792Å b: 135.95Å c: 136.908Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.223 0.22 0.28
Expression system: Homo sapiens

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