› 7ls2

Electron Microscopy
3.1Å resolution

80S ribosome from mouse bound to eEF2 (Class I)

Released:
DOI: 10.2210/pdb7ls2/pdb
PDB entry 7ls2 coloured by chain, front view.
PDB entry 7ls2 coloured by chain, side view.
PDB entry 7ls2 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance.
Smith PR, Loerch S, Kunder N, Stanowick AD, Lou TF, Campbell ZT
Nat Commun 12 6789 (2021)
PMID: 34815424
Related structures: EMD-23501

Function and Biology Details

Reaction catalysed: 
The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero 85-mer (preferred)
PDBe Complex ID:
PDB-CPX-236911 (preferred)
Entry contents:
80 distinct polypeptide molecules
5 distinct RNA molecules
Macromolecules (85 distinct):
Large ribosomal subunit protein uL30 Chain: A1
Molecule details ›
Chain: A1
Length: 270 amino acids
Theoretical weight: 31.49 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P14148 (Residues: 1-270; Coverage: 100%)
Gene name: Rpl7
Sequence domains:
Large ribosomal subunit protein eL8 Chain: B1
Molecule details ›
Chain: B1
Length: 266 amino acids
Theoretical weight: 30.04 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P12970 (Residues: 1-266; Coverage: 100%)
Gene names: Rpl7a, Surf-3, Surf3
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Large ribosomal subunit protein uL6 Chain: C1
Molecule details ›
Chain: C1
Length: 192 amino acids
Theoretical weight: 21.92 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P51410 (Residues: 1-192; Coverage: 100%)
Gene name: Rpl9
Sequence domains: Ribosomal protein L6
Large ribosomal subunit protein uL16-like Chain: D1
Molecule details ›
Chain: D1
Length: 214 amino acids
Theoretical weight: 24.61 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P86048 (Residues: 1-214; Coverage: 100%)
Gene name: Rpl10l
Sequence domains: Ribosomal protein L16p/L10e
Large ribosomal subunit protein uL5 Chain: E1
Molecule details ›
Chain: E1
Length: 178 amino acids
Theoretical weight: 20.29 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q9CXW4 (Residues: 1-178; Coverage: 100%)
Gene name: Rpl11
Sequence domains:
Large ribosomal subunit protein eL13 Chain: F1
Molecule details ›
Chain: F1
Length: 211 amino acids
Theoretical weight: 24.36 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P47963 (Residues: 1-211; Coverage: 100%)
Gene name: Rpl13
Sequence domains: Ribosomal protein L13e
Large ribosomal subunit protein eL14 Chain: G1
Molecule details ›
Chain: G1
Length: 217 amino acids
Theoretical weight: 23.62 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q9CR57 (Residues: 1-217; Coverage: 100%)
Gene name: Rpl14
Sequence domains: Ribosomal protein L14
Large ribosomal subunit protein eL15 Chain: H1
Molecule details ›
Chain: H1
Length: 204 amino acids
Theoretical weight: 24.21 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q9CZM2 (Residues: 1-204; Coverage: 100%)
Gene name: Rpl15
Sequence domains: Ribosomal L15
Large ribosomal subunit protein uL2 Chain: D2
Molecule details ›
Chain: D2
Length: 257 amino acids
Theoretical weight: 28.09 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62918 (Residues: 1-257; Coverage: 100%)
Gene name: Rpl8
Sequence domains:
Large ribosomal subunit protein uL3 Chain: E2
Molecule details ›
Chain: E2
Length: 403 amino acids
Theoretical weight: 46.21 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P27659 (Residues: 1-403; Coverage: 100%)
Gene name: Rpl3
Sequence domains: Ribosomal protein L3
Large ribosomal subunit protein uL4 Chain: F2
Molecule details ›
Chain: F2
Length: 419 amino acids
Theoretical weight: 47.27 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q9D8E6 (Residues: 1-419; Coverage: 100%)
Gene name: Rpl4
Sequence domains:
Large ribosomal subunit protein uL18 Chain: G2
Molecule details ›
Chain: G2
Length: 297 amino acids
Theoretical weight: 34.46 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P47962 (Residues: 1-297; Coverage: 100%)
Gene name: Rpl5
Sequence domains:
Large ribosomal subunit protein eL6 Chain: H2
Molecule details ›
Chain: H2
Length: 296 amino acids
Theoretical weight: 33.59 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P47911 (Residues: 1-296; Coverage: 100%)
Gene name: Rpl6
Sequence domains:
Large ribosomal subunit protein uL13 Chain: I2
Molecule details ›
Chain: I2
Length: 203 amino acids
Theoretical weight: 23.52 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P19253 (Residues: 1-203; Coverage: 100%)
Gene names: P198, Rpl13a, Tstap198-7
Sequence domains: Ribosomal protein L13
Large ribosomal subunit protein uL22 Chain: J2
Molecule details ›
Chain: J2
Length: 184 amino acids
Theoretical weight: 21.47 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q9CPR4 (Residues: 1-184; Coverage: 100%)
Gene name: Rpl17
Sequence domains: Ribosomal protein L22p/L17e
Large ribosomal subunit protein eL18 Chain: K2
Molecule details ›
Chain: K2
Length: 188 amino acids
Theoretical weight: 21.7 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P35980 (Residues: 1-188; Coverage: 100%)
Gene name: Rpl18
Sequence domains: Ribosomal protein 60S L18 and 50S L18e
Large ribosomal subunit protein eL19 Chain: L2
Molecule details ›
Chain: L2
Length: 196 amino acids
Theoretical weight: 23.54 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P84099 (Residues: 1-196; Coverage: 100%)
Gene name: Rpl19
Sequence domains: Ribosomal protein L19e
Large ribosomal subunit protein eL20 Chain: M2
Molecule details ›
Chain: M2
Length: 176 amino acids
Theoretical weight: 20.78 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62717 (Residues: 1-176; Coverage: 100%)
Gene name: Rpl18a
Sequence domains: Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
Large ribosomal subunit protein eL21 Chain: N2
Molecule details ›
Chain: N2
Length: 160 amino acids
Theoretical weight: 18.61 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: O09167 (Residues: 1-160; Coverage: 100%)
Gene name: Rpl21
Sequence domains: Ribosomal protein L21e
Large ribosomal subunit protein eL22 Chain: O2
Molecule details ›
Chain: O2
Length: 128 amino acids
Theoretical weight: 14.78 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P67984 (Residues: 1-128; Coverage: 100%)
Gene name: Rpl22
Sequence domains: Ribosomal L22e protein family
Large ribosomal subunit protein uL14 Chain: P2
Molecule details ›
Chain: P2
Length: 140 amino acids
Theoretical weight: 14.89 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62830 (Residues: 1-140; Coverage: 100%)
Gene name: Rpl23
Sequence domains: Ribosomal protein L14p/L23e
Large ribosomal subunit protein eL24 Chain: Q2
Molecule details ›
Chain: Q2
Length: 157 amino acids
Theoretical weight: 17.83 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q8BP67 (Residues: 1-157; Coverage: 100%)
Gene name: Rpl24
Sequence domains: Ribosomal protein L24e
Large ribosomal subunit protein uL23 Chain: R2
Molecule details ›
Chain: R2
Length: 156 amino acids
Theoretical weight: 17.74 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62751 (Residues: 1-156; Coverage: 100%)
Gene name: Rpl23a
Sequence domains:
Large ribosomal subunit protein uL24 Chain: S2
Molecule details ›
Chain: S2
Length: 145 amino acids
Theoretical weight: 17.3 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P61255 (Residues: 1-145; Coverage: 100%)
Gene name: Rpl26
Sequence domains:
Large ribosomal subunit protein eL27 Chain: T2
Molecule details ›
Chain: T2
Length: 136 amino acids
Theoretical weight: 15.84 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P61358 (Residues: 1-136; Coverage: 100%)
Gene name: Rpl27
Sequence domains:
Large ribosomal subunit protein uL15 Chain: U2
Molecule details ›
Chain: U2
Length: 148 amino acids
Theoretical weight: 16.65 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P14115 (Residues: 1-148; Coverage: 100%)
Gene name: Rpl27a
Sequence domains: Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
Large ribosomal subunit protein eL29 Chain: V2
Molecule details ›
Chain: V2
Length: 160 amino acids
Theoretical weight: 17.64 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P47915 (Residues: 1-160; Coverage: 100%)
Gene names: Rpl29, Rpl43
Sequence domains: Ribosomal L29e protein family
Large ribosomal subunit protein eL30 Chain: W2
Molecule details ›
Chain: W2
Length: 115 amino acids
Theoretical weight: 12.81 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62889 (Residues: 1-115; Coverage: 100%)
Gene name: Rpl30
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Large ribosomal subunit protein eL31 Chain: X2
Molecule details ›
Chain: X2
Length: 125 amino acids
Theoretical weight: 14.49 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62900 (Residues: 1-125; Coverage: 100%)
Gene name: Rpl31
Sequence domains: Ribosomal protein L31e
Large ribosomal subunit protein eL32 Chain: Y2
Molecule details ›
Chain: Y2
Length: 135 amino acids
Theoretical weight: 15.9 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62911 (Residues: 1-135; Coverage: 100%)
Gene name: Rpl32
Sequence domains: Ribosomal protein L32
Large ribosomal subunit protein eL33 Chain: Z2
Molecule details ›
Chain: Z2
Length: 110 amino acids
Theoretical weight: 12.58 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: O55142 (Residues: 1-110; Coverage: 100%)
Gene name: Rpl35a
Sequence domains: Ribosomal protein L35Ae
Large ribosomal subunit protein eL34 Chain: a2
Molecule details ›
Chain: a2
Length: 117 amino acids
Theoretical weight: 13.33 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q9D1R9 (Residues: 1-117; Coverage: 100%)
Gene name: Rpl34
Sequence domains: Ribosomal protein L34e
Large ribosomal subunit protein uL29 Chain: b2
Molecule details ›
Chain: b2
Length: 123 amino acids
Theoretical weight: 14.6 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q6ZWV7 (Residues: 1-123; Coverage: 100%)
Gene name: Rpl35
Sequence domains: Ribosomal L29 protein
Large ribosomal subunit protein eL36 Chain: c2
Molecule details ›
Chain: c2
Length: 105 amino acids
Theoretical weight: 12.25 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P47964 (Residues: 1-105; Coverage: 100%)
Gene name: Rpl36
Sequence domains: Ribosomal protein L36e
Large ribosomal subunit protein eL37 Chain: d2
Molecule details ›
Chain: d2
Length: 97 amino acids
Theoretical weight: 11.11 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q9D823 (Residues: 1-97; Coverage: 100%)
Gene name: Rpl37
Sequence domains: Ribosomal protein L37e
Large ribosomal subunit protein eL38 Chain: e2
Molecule details ›
Chain: e2
Length: 70 amino acids
Theoretical weight: 8.22 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q9JJI8 (Residues: 1-70; Coverage: 100%)
Gene name: Rpl38
Sequence domains: Ribosomal L38e protein family
Large ribosomal subunit protein eL39 Chain: f2
Molecule details ›
Chain: f2
Length: 51 amino acids
Theoretical weight: 6.43 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62892 (Residues: 1-51; Coverage: 100%)
Gene name: Rpl39
Sequence domains: Ribosomal L39 protein
Ubiquitin-ribosomal protein eL40 fusion protein Chain: g2
Molecule details ›
Chain: g2
Length: 128 amino acids
Theoretical weight: 14.77 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62984 (Residues: 1-128; Coverage: 100%)
Gene names: Uba52, Ubcep2
Sequence domains:
Small ribosomal subunit protein eS32 Chain: h2
Molecule details ›
Chain: h2
Length: 25 amino acids
Theoretical weight: 3.47 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62947 (Residues: 1-25; Coverage: 100%)
Gene name: Rpl41
Sequence domains: Ribosomal protein L41
Large ribosomal subunit protein eL42 Chain: i2
Molecule details ›
Chain: i2
Length: 106 amino acids
Theoretical weight: 12.48 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P83882 (Residues: 1-106; Coverage: 100%)
Gene names: Rpl36a, Rpl44
Sequence domains: Ribosomal protein L44
Large ribosomal subunit protein eL43 Chain: j2
Molecule details ›
Chain: j2
Length: 92 amino acids
Theoretical weight: 10.3 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P61514 (Residues: 1-92; Coverage: 100%)
Gene name: Rpl37a
Sequence domains: Ribosomal L37ae protein family
Large ribosomal subunit protein eL28 Chain: k2
Molecule details ›
Chain: k2
Length: 137 amino acids
Theoretical weight: 15.77 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P41105 (Residues: 1-137; Coverage: 100%)
Gene name: Rpl28
Sequence domains: Ribosomal L28e protein family
Small ribosomal subunit protein eS1 Chain: p2
Molecule details ›
Chain: p2
Length: 264 amino acids
Theoretical weight: 29.94 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P97351 (Residues: 1-264; Coverage: 100%)
Gene names: Rps3a, Rps3a1
Sequence domains: Ribosomal S3Ae family
Small ribosomal subunit protein uS3 Chain: q2
Molecule details ›
Chain: q2
Length: 243 amino acids
Theoretical weight: 26.72 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62908 (Residues: 1-243; Coverage: 100%)
Gene name: Rps3
Sequence domains:
Small ribosomal subunit protein eS4 Chain: r2
Molecule details ›
Chain: r2
Length: 263 amino acids
Theoretical weight: 29.65 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62702 (Residues: 1-263; Coverage: 100%)
Gene names: Rps4, Rps4x
Sequence domains:
Small ribosomal subunit protein uS17 Chain: w2
Molecule details ›
Chain: w2
Length: 158 amino acids
Theoretical weight: 18.47 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62281 (Residues: 1-158; Coverage: 100%)
Gene name: Rps11
Sequence domains:
Small ribosomal subunit protein eS17 Chain: z2
Molecule details ›
Chain: z2
Length: 135 amino acids
Theoretical weight: 15.55 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P63276 (Residues: 1-135; Coverage: 100%)
Gene name: Rps17
Sequence domains: Ribosomal S17
Small ribosomal subunit protein uS2 Chain: o2
Molecule details ›
Chain: o2
Length: 295 amino acids
Theoretical weight: 32.87 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P14206 (Residues: 1-295; Coverage: 100%)
Gene names: Lamr1, P40-8, Rpsa
Sequence domains:
Small ribosomal subunit protein uS7 Chain: s2
Molecule details ›
Chain: s2
Length: 204 amino acids
Theoretical weight: 22.93 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P97461 (Residues: 1-204; Coverage: 100%)
Gene name: Rps5
Sequence domains: Ribosomal protein S7p/S5e
Small ribosomal subunit protein eS10 Chain: v2
Molecule details ›
Chain: v2
Length: 165 amino acids
Theoretical weight: 18.95 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P63325 (Residues: 1-165; Coverage: 100%)
Gene name: Rps10
Sequence domains: Plectin/S10 domain
Small ribosomal subunit protein uS19 Chain: x2
Molecule details ›
Chain: x2
Length: 145 amino acids
Theoretical weight: 17.08 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62843 (Residues: 1-145; Coverage: 100%)
Gene names: Rig, Rps15
Sequence domains: Ribosomal protein S19
Small ribosomal subunit protein uS9 Chain: y2
Molecule details ›
Chain: y2
Length: 146 amino acids
Theoretical weight: 16.48 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P14131 (Residues: 1-146; Coverage: 100%)
Gene name: Rps16
Sequence domains: Ribosomal protein S9/S16
Small ribosomal subunit protein uS13 Chain: A3
Molecule details ›
Chain: A3
Length: 152 amino acids
Theoretical weight: 17.76 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62270 (Residues: 1-152; Coverage: 100%)
Gene name: Rps18
Sequence domains: Ribosomal protein S13/S18
Small ribosomal subunit protein eS19 Chain: B3
Molecule details ›
Chain: B3
Length: 145 amino acids
Theoretical weight: 16.12 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q9CZX8 (Residues: 1-145; Coverage: 100%)
Gene name: Rps19
Sequence domains: Ribosomal protein S19e
Small ribosomal subunit protein uS10 Chain: C3
Molecule details ›
Chain: C3
Length: 119 amino acids
Theoretical weight: 13.4 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P60867 (Residues: 1-119; Coverage: 100%)
Gene name: Rps20
Sequence domains: Ribosomal protein S10p/S20e
Small ribosomal subunit protein eS21 Chain: D3
Molecule details ›
Chain: D3
Length: 83 amino acids
Theoretical weight: 9.15 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q9CQR2 (Residues: 1-83; Coverage: 100%)
Gene name: Rps21
Sequence domains: Ribosomal protein S21e
Small ribosomal subunit protein uS12 Chain: E3
Molecule details ›
Chain: E3
Length: 143 amino acids
Theoretical weight: 15.84 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62267 (Residues: 1-143; Coverage: 100%)
Gene name: Rps23
Sequence domains: Ribosomal protein S12/S23
Small ribosomal subunit protein eS26 Chain: F3
Molecule details ›
Chain: F3
Length: 115 amino acids
Theoretical weight: 13.05 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62855 (Residues: 1-115; Coverage: 100%)
Gene name: Rps26
Sequence domains: Ribosomal protein S26e
Small ribosomal subunit protein eS28 Chain: G3
Molecule details ›
Chain: G3
Length: 69 amino acids
Theoretical weight: 7.86 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62858 (Residues: 1-69; Coverage: 100%)
Gene name: Rps28
Sequence domains: Ribosomal protein S28e
Small ribosomal subunit protein uS14 Chain: H3
Molecule details ›
Chain: H3
Length: 56 amino acids
Theoretical weight: 6.69 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62274 (Residues: 1-56; Coverage: 100%)
Gene name: Rps29
Sequence domains: Ribosomal protein S14p/S29e
Small ribosomal subunit protein RACK1 Chain: I3
Molecule details ›
Chain: I3
Length: 317 amino acids
Theoretical weight: 35.12 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P68040 (Residues: 1-317; Coverage: 100%)
Gene names: Gnb2-rs1, Gnb2l1, Rack1
Sequence domains: WD domain, G-beta repeat
Small ribosomal subunit protein uS5 Chain: J3
Molecule details ›
Chain: J3
Length: 293 amino acids
Theoretical weight: 31.28 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P25444 (Residues: 1-293; Coverage: 100%)
Gene names: Llrep3, Rps2, Rps4
Sequence domains:
Small ribosomal subunit protein eS6 Chain: K3
Molecule details ›
Chain: K3
Length: 249 amino acids
Theoretical weight: 28.75 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62754 (Residues: 1-249; Coverage: 100%)
Gene name: Rps6
Sequence domains: Ribosomal protein S6e
Small ribosomal subunit protein uS4 Chain: L3
Molecule details ›
Chain: L3
Length: 194 amino acids
Theoretical weight: 22.64 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q6ZWN5 (Residues: 1-194; Coverage: 100%)
Gene name: Rps9
Sequence domains:
Small ribosomal subunit protein eS12 Chain: M3
Molecule details ›
Chain: M3
Length: 132 amino acids
Theoretical weight: 14.55 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P63323 (Residues: 1-132; Coverage: 100%)
Gene name: Rps12
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Small ribosomal subunit protein uS15 Chain: N3
Molecule details ›
Chain: N3
Length: 151 amino acids
Theoretical weight: 17.26 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62301 (Residues: 1-151; Coverage: 100%)
Gene name: Rps13
Sequence domains:
Small ribosomal subunit protein uS11 Chain: O3
Molecule details ›
Chain: O3
Length: 151 amino acids
Theoretical weight: 16.3 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62264 (Residues: 1-151; Coverage: 100%)
Gene name: Rps14
Sequence domains: Ribosomal protein S11
Small ribosomal subunit protein uS8 Chain: P3
Molecule details ›
Chain: P3
Length: 130 amino acids
Theoretical weight: 14.87 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62245 (Residues: 1-130; Coverage: 100%)
Gene name: Rps15a
Sequence domains: Ribosomal protein S8
Small ribosomal subunit protein eS24 Chain: Q3
Molecule details ›
Chain: Q3
Length: 133 amino acids
Theoretical weight: 15.46 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62849 (Residues: 1-133; Coverage: 100%)
Gene name: Rps24
Sequence domains: Ribosomal protein S24e
Small ribosomal subunit protein eS25 Chain: R3
Molecule details ›
Chain: R3
Length: 125 amino acids
Theoretical weight: 13.78 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62852 (Residues: 1-125; Coverage: 100%)
Gene name: Rps25
Sequence domains: S25 ribosomal protein
Small ribosomal subunit protein eS27-like Chain: S3
Molecule details ›
Chain: S3
Length: 84 amino acids
Theoretical weight: 9.5 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q6ZWY3 (Residues: 1-84; Coverage: 100%)
Gene name: Rps27l
Sequence domains: Ribosomal protein S27
Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein Chain: T3
Molecule details ›
Chain: T3
Length: 133 amino acids
Theoretical weight: 14.44 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62862 (Residues: 1-133; Coverage: 100%)
Gene name: Fau
Sequence domains: Ribosomal protein S30
Ubiquitin-ribosomal protein eS31 fusion protein Chain: U3
Molecule details ›
Chain: U3
Length: 156 amino acids
Theoretical weight: 17.99 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62983 (Residues: 1-156; Coverage: 100%)
Gene names: Rps27a, Uba80, Ubcep1
Sequence domains:
Elongation factor 2 Chain: m
Molecule details ›
Chain: m
Length: 858 amino acids
Theoretical weight: 95.58 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P58252 (Residues: 1-858; Coverage: 100%)
Gene name: Eef2
Sequence domains:
Large ribosomal subunit protein uL10 Chain: j
Molecule details ›
Chain: j
Length: 317 amino acids
Theoretical weight: 34.25 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P14869 (Residues: 1-317; Coverage: 100%)
Gene names: Arbp, Rplp0
Sequence domains:
Large ribosomal subunit protein uL11 Chain: k
Molecule details ›
Chain: k
Length: 165 amino acids
Theoretical weight: 17.83 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P35979 (Residues: 1-165; Coverage: 100%)
Gene name: Rpl12
Sequence domains:
SERPINE1 mRNA-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 386 amino acids
Theoretical weight: 42.32 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q9CY58 (Residues: 1-407; Coverage: 95%)
Gene names: Pairbp1, Serbp1
Sequence domains:
Small ribosomal subunit protein eS7 Chain: t
Molecule details ›
Chain: t
Length: 194 amino acids
Theoretical weight: 22.17 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62082 (Residues: 1-194; Coverage: 100%)
Gene name: Rps7
Sequence domains: Ribosomal protein S7e
Small ribosomal subunit protein eS8 Chain: u
Molecule details ›
Chain: u
Length: 208 amino acids
Theoretical weight: 24.26 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P62242 (Residues: 1-208; Coverage: 100%)
Gene name: Rps8
Sequence domains: Ribosomal protein S8e
Large ribosomal subunit protein uL1 Chain: L1
Molecule details ›
Chain: L1
Length: 217 amino acids
Theoretical weight: 24.97 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P53026 (Residues: 1-217; Coverage: 100%)
Gene names: Nedd-6, Nedd6, Rpl10a
Sequence domains: Ribosomal protein L1p/L10e family
28S ribosomal RNA Chain: A2
Molecule details ›
Chain: A2
Length: 4731 nucleotides
Theoretical weight: 1532.1 KDa
Sequence domains: Eukaryotic large subunit ribosomal RNA
5S ribosomal RNA Chain: B2
Molecule details ›
Chain: B2
Length: 121 nucleotides
Theoretical weight: 39 KDa
Sequence domains: 5S ribosomal RNA
5.8S ribosomal RNA Chain: C2
Molecule details ›
Chain: C2
Length: 156 nucleotides
Theoretical weight: 50.16 KDa
Sequence domains: 5.8S ribosomal RNA
18S Ribosomal RNA Chain: m2
Molecule details ›
Chain: m2
Length: 1871 nucleotides
Theoretical weight: 603.71 KDa
Sequence domains: Eukaryotic small subunit ribosomal RNA
tRNA Chain: n2
Molecule details ›
Chain: n2
Length: 75 nucleotides
Theoretical weight: 24.23 KDa
Sequence domains: tRNA

Ligands and Environments

3 bound ligands:
Ligand ZN 7 x ZN
Ligand MG 1 x MG
Ligand GDP 1 x GDP
23 modified residues:
Ligand B9B 2 x B9B
Ligand OMG 17 x OMG
Ligand A2M 17 x A2M
Ligand 2MG 3 x 2MG
Ligand B8Q 1 x B8Q
Ligand PSU 20 x PSU
Ligand G7M 3 x G7M
Ligand I4U 2 x I4U
Ligand E7G 2 x E7G
Ligand UR3 3 x UR3
Ligand P7G 2 x P7G
Ligand OMC 10 x OMC
Ligand B9H 1 x B9H
Ligand 5MC 3 x 5MC
Ligand B8W 1 x B8W
Ligand 6MZ 1 x 6MZ
Ligand OMU 4 x OMU
Ligand E6G 1 x E6G
Ligand MHG 1 x MHG
Ligand 1MA 1 x 1MA
Ligand B8T 1 x B8T
Ligand MLZ 2 x MLZ
Ligand DDE 1 x DDE

Experiments and Validation Details

Entry percentile scores
Resolution: 3.1Å
Relevant EMDB volumes: EMD-23501

Quick links

Citations

3 review citations

Recent advances and current trends in cryo-electron microscopy.
Guaita et al. (2022)
2 more

1 mention without citation

Systematic compositional analysis of exosomal extracellular vesicles produced by cells undergoing apoptosis, necroptosis and ferroptosis.
Cappe et al. (2023)