› 7lsb

X-ray diffraction
2.49Å resolution

Structure of B1, a monoclonal VEGFR2 antibody parental of KD035

Released:
DOI: 10.2210/pdb7lsb/pdb
PDB entry 7lsb coloured by chain, front view.
PDB entry 7lsb coloured by chain, side view.
PDB entry 7lsb coloured by chain, top view.
Source organism: Homo sapiens
Entry author: Depetris RS

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-214385 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
B1 Fab heavy chain Chain: B
Molecule details ›
Chain: B
Length: 218 amino acids
Theoretical weight: 23.13 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
B1 Fab light chain Chain: D
Molecule details ›
Chain: D
Length: 212 amino acids
Theoretical weight: 22.73 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: RIGAKU
Spacegroup: P21
Unit cell:
a: 55.691Å b: 66.416Å c: 66.543Å
α: 90° β: 101.93° γ: 90°
R-values:
R R work R free
0.191 0.184 0.254
Expression system: Homo sapiens

Quick links