› 7m3n

Electron Microscopy
2.4Å resolution

Canine parvovirus and Fab14 asymmetric reconstruction

Released:
DOI: 10.2210/pdb7m3n/pdb
PDB entry 7m3n coloured by chain, front view.
PDB entry 7m3n coloured by chain, side view.
PDB entry 7m3n coloured by chain, top view.
Source organisms:
Primary publication:
High-resolution asymmetric structure of a Fab-virus complex reveals overlap with the receptor binding site.
Goetschius DJ, Hartmann SR, Organtini LJ, Callaway H, Huang K, Bator CM, Ashley RE, Makhov AM, Conway JF, Parrish CR, Hafenstein SL
Proc Natl Acad Sci U S A 118 (2021)
PMID: 34074770
Related structures: EMD-23658

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-210703 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
CPV Fab14 light chain Chain: L
Molecule details ›
Chain: L
Length: 108 amino acids
Theoretical weight: 11.98 KDa
Source organism: Mus musculus
CPV Fab14 heavy chain Chain: H
Molecule details ›
Chain: H
Length: 119 amino acids
Theoretical weight: 13.1 KDa
Source organism: Mus musculus
Capsid protein VP1 Chain: A
Molecule details ›
Chain: A
Length: 584 amino acids
Theoretical weight: 64.71 KDa
Source organism: Canine parvovirus
UniProt:
  • Canonical: P17455 (Residues: 144-727; Coverage: 80%)
Sequence domains: Parvovirus coat protein VP2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.4Å
Relevant EMDB volumes: EMD-23658

Quick links

Citations

1 review citation

The Structures and Functions of Parvovirus Capsids and Missing Pieces: the Viral DNA and Its Packaging, Asymmetrical Features, Nonprotein Components, and Receptor or Antibody Binding and Interactions.
López-Astacio et al. (2023)
8 other articles