Function and Biology Details
Reaction catalysed:
Propanoyl-CoA + 6 (2S)-methylmalonyl-CoA + 6 NADPH = 6-deoxyerythronolide B + 7 CoA + 6 CO(2) + H(2)O + 6 NADP(+)
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-211898 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
6-deoxyerythronolide-B synthase EryA1, modules 1 and 2; 6-deoxyerythronolide-B synthase EryA2, modules 3 and 4; 6-deoxyerythronolide-B synthase EryA3, modules 5 and 6
Molecule details ›
Chains: A, B
Length: 1777 amino acids
Theoretical weight: 187.84 KDa
Source organism: Saccharopolyspora erythraea
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 1777 amino acids
Theoretical weight: 187.84 KDa
Source organism: Saccharopolyspora erythraea
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q03132 (Residues: 2-922; Coverage: 26%) - Canonical: Q03131 (Residues: 1404-1962; Coverage: 16%)
- Canonical: Q03133 (Residues: 2896-3172; Coverage: 9%)
Sequence domains:
