Function and Biology Details
Reactions catalysed:
O(4)-succinyl-L-homoserine + L-cysteine = L-cystathionine + succinate
(1a) L-cystathionine = L-cysteine + 2-aminobut-2-enoate
L-cystathionine + H(2)O = L-homocysteine + NH(3) + pyruvate
Biochemical function:
Biological process:
Cellular component:
Sequence domain:
Structure analysis Details
Assembly composition:
homo tetramer (preferred)
Assembly name:
Cystathionine gamma-synthase (preferred)
PDBe Complex ID:
PDB-CPX-102039 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cystathionine gamma-synthase
Molecule details ›
Chain: H
Length: 380 amino acids
Theoretical weight: 41.46 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Cys/Met metabolism PLP-dependent enzyme
Length: 380 amino acids
Theoretical weight: 41.46 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
A0A0H3K724 (Residues: 2-380; Coverage: 100%)
Sequence domains: Cys/Met metabolism PLP-dependent enzyme
Ligands and Environments
Experiments and Validation Details
wwPDB Validation report is not available for this entry.
X-ray source:
NSLS-II BEAMLINE 17-ID-2
Spacegroup:
I4122
Expression system: Escherichia coli BL21(DE3)
