› 7o2k

Solution NMR

NMR solution structue of cytotoxin 2 from Naja Kaouthia

Released:
DOI: 10.2210/pdb7o2k/pdb
PDB entry 7o2k coloured by chain, ensemble of 20 models, front view.
PDB entry 7o2k coloured by chain, ensemble of 20 models, side view.
PDB entry 7o2k coloured by chain, ensemble of 20 models, top view.
Source organism: Naja kaouthia
Primary publication:
The omega-loop of cobra cytotoxins tolerates multiple amino acid substitutions.
Dubinnyi MA, Dubovskii PV, Starkov VG, Utkin YN
Biochem Biophys Res Commun 558 141-146 (2021)
PMID: 33915327

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134317 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytotoxin 2 Chain: A
Molecule details ›
Chain: A
Length: 60 amino acids
Theoretical weight: 6.76 KDa
Source organism: Naja kaouthia
UniProt:
  • Canonical: P01445 (Residues: 1-60; Coverage: 100%)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 83%
Refinement method: torsion angle dynamics

Quick links

Citations

1 citations in other articles

Membrane-Disrupting Activity of Cobra Cytotoxins Is Determined by Configuration of the N-Terminal Loop.
Dubovskii et al. (2022)

1 mention without citation

Variability in the Spatial Structure of the Central Loop in Cobra Cytotoxins Revealed by X-ray Analysis and Molecular Modeling.
Dubovskii et al. (2022)