› 7oex

X-ray diffraction
1.51Å resolution

Crystal structure of RBBP9 in complex with phenylalanine

Released:
DOI: 10.2210/pdb7oex/pdb
PDB entry 7oex coloured by chain, front view.
PDB entry 7oex coloured by chain, side view.
PDB entry 7oex coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Mechanism-based traps enable protease and hydrolase substrate discovery.
Tang S, Beattie AT, Kafkova L, Petris G, Huguenin-Dezot N, Fiedler M, Freeman M, Chin JW
Nature 602 701-707 (2022)
PMID: 35173328

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131152 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine hydrolase RBBP9 Chains: A, B
Molecule details ›
Chains: A, B
Length: 194 amino acids
Theoretical weight: 22.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O75884 (Residues: 1-186; Coverage: 100%)
Gene names: BOG, RBBP10, RBBP9
Sequence domains: Serine hydrolase

Ligands and Environments

1 bound ligand:
Ligand PHE 2 x PHE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P21
Unit cell:
a: 36.956Å b: 130.127Å c: 38.993Å
α: 90° β: 115.24° γ: 90°
R-values:
R R work R free
0.163 0.161 0.197
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Update of the Pyrrolysyl-tRNA Synthetase/tRNAPyl Pair and Derivatives for Genetic Code Expansion.
Gong et al. (2023)
1 more