› 7omn

X-ray diffraction
1.7Å resolution

Anti-EphA1 JD1-1 VH domain

Released:
DOI: 10.2210/pdb7omn/pdb
Model geometry
Fit model/data
PDB entry 7omn coloured by chain, front view.
PDB entry 7omn coloured by chain, side view.
PDB entry 7omn coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Systematic Engineering of Optimized Autonomous Heavy-Chain Variable Domains.
Nilvebrant J, Ereño-Orbea J, Gorelik M, Julian MC, Tessier PM, Julien JP, Sidhu SS
J Mol Biol 433 167241 (2021)
PMID: 34508727

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-214417 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
JD1-1 VH domain Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 125 amino acids
Theoretical weight: 13.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli

Ligands and Environments

2 bound ligands:
Ligand IMD 6 x IMD
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P64
Unit cell:
a: 131.87Å b: 131.87Å c: 49.679Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.204 0.203 0.222
Expression system: Escherichia coli

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Citations

3 citation in other articles

Construction of Synthetic Antibody Phage Display Libraries.
Giang et al. (2023)
2 more