› 7oxs

X-ray diffraction
1.91Å resolution

1.91 A crystal structure of DNA/2'-O-methyl-RNA heteroduplex

Released:
DOI: 10.2210/pdb7oxs/pdb
PDB entry 7oxs coloured by chain, front view.
PDB entry 7oxs coloured by chain, side view.
PDB entry 7oxs coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
First High-Resolution Crystal Structures of DNA:2'-O-Methyl-RNA Heteroduplexes
Dolot R, Maciaszek A, Mikolajczyk B, Nawrot B
Crystals (2022)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-121761 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
DNA (5'-D(*GP*TP*CP*TP*CP*CP*TP*AP*G)-3') Chains: A, C
Molecule details ›
Chains: A, C
Length: 9 nucleotides
Theoretical weight: 2.71 KDa
Source organism: synthetic construct
Expression system: Not provided
RNA (5'-R(*(OMC)P*(OMU)P*(A2M)P*(OMG)P*(OMG)P*(A2M)P*(OMG)P*(A2M)P*(OMC))-3') Chains: B, D
Molecule details ›
Chains: B, D
Length: 9 nucleotides
Theoretical weight: 3.02 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand SO4 2 x SO4
4 modified residues:
Ligand OMC 4 x OMC
Ligand OMU 2 x OMU
Ligand A2M 6 x A2M
Ligand OMG 6 x OMG

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: P3221
Unit cell:
a: 56.13Å b: 56.13Å c: 76.26Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.185 0.184 0.195
Expression system: Not provided

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