› 7p7d

X-ray diffraction
1.45Å resolution

Rabbit muscle Glycogen Phosphorylase T state

Released:
DOI: 10.2210/pdb7p7d/pdb
PDB entry 7p7d coloured by chain, front view.
PDB entry 7p7d coloured by chain, side view.
PDB entry 7p7d coloured by chain, top view.
Source organism: Oryctolagus cuniculus
Primary publication:
Glycogen phosphorylase revisited: extending the resolution of the R- and T-state structures of the free enzyme and in complex with allosteric activators.
Leonidas DD, Zographos SE, Tsitsanou KE, Skamnaki VT, Stravodimos G, Kyriakis E
Acta Crystallogr F Struct Biol Commun 77 303-311 (2021)
PMID: 34473107

Function and Biology Details

Reaction catalysed: 
((1->4)-alpha-D-glucosyl)(n) + phosphate = ((1->4)-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132556 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glycogen phosphorylase, muscle form Chain: A
Molecule details ›
Chain: A
Length: 830 amino acids
Theoretical weight: 96.2 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P00489 (Residues: 8-837; Coverage: 99%)
Gene name: PYGM
Sequence domains: Carbohydrate phosphorylase

Ligands and Environments

1 bound ligand:
Ligand DMS 21 x DMS
2 modified residues:
Ligand CSO 1 x CSO
Ligand LLP 1 x LLP

Experiments and Validation Details

Entry percentile scores
X-ray source: PETRA III, EMBL c/o DESY BEAMLINE P13 (MX1)
Spacegroup: P43212
Unit cell:
a: 126.279Å b: 126.279Å c: 115.361Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.132 0.13 0.17

Quick links

Citations

3 citation in other articles

Structural Basis of Sequential and Concerted Cooperativity.
Morea et al. (2022)
2 more

1 mention without citation

Glycogen phosphorylase revisited: extending the resolution of the R- and T-state structures of the free enzyme and in complex with allosteric activators.
Leonidas et al. (2021)