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7pa8

X-ray diffraction
3.15Å resolution

JC polyomavirus VP1 in complex with Fab 27C2

Released:
Model geometry
Fit model/data
Source organisms:
Entry authors: Stroeh LJ, Harprecht C, Freytag J, Stehle T

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero pentadecamer (preferred)
PDBe Complex ID:
PDB-CPX-225018 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Major capsid protein VP1 Chains: AAA, BBB, CCC, DDD, EEE
Molecule details ›
Chains: AAA, BBB, CCC, DDD, EEE
Length: 272 amino acids
Theoretical weight: 30.08 KDa
Source organism: JC polyomavirus
Expression system: Escherichia coli
UniProt:
  • Canonical: P03089 (Residues: 23-290; Coverage: 76%)
Sequence domains: Polyomavirus coat protein
Fab 27C2 light chain Chains: FFF, GGG, III, KKK, MMM
Molecule details ›
Chains: FFF, GGG, III, KKK, MMM
Length: 212 amino acids
Theoretical weight: 22.23 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Fab 27C2 heavy chain Chains: HHH, JJJ, LLL, NNN, YYY

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P21
Unit cell:
a: 137.07Å b: 110.44Å c: 158.21Å
α: 90° β: 93.115° γ: 90°
R-values:
R R work R free
0.213 0.212 0.241
Expression systems:
  • Escherichia coli
  • Homo sapiens