› 7qhi

X-ray diffraction
2.3Å resolution

Crystal structure of cytotoxin 13 from Naja naja, hexagonal form

Released:
DOI: 10.2210/pdb7qhi/pdb
PDB entry 7qhi coloured by chain, front view.
PDB entry 7qhi coloured by chain, side view.
PDB entry 7qhi coloured by chain, top view.
Source organism: Naja naja
Primary publication:
Variability in the Spatial Structure of the Central Loop in Cobra Cytotoxins Revealed by X-ray Analysis and Molecular Modeling.
Dubovskii PV, Dubova KM, Bourenkov G, Starkov VG, Konshina AG, Efremov RG, Utkin YN, Samygina VR
Toxins (Basel) 14 (2022)
PMID: 35202176

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-102758 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
UPAR/Ly6 domain-containing protein Chains: AAA, BBB, CCC
Molecule details ›
Chains: AAA, BBB, CCC
Length: 60 amino acids
Theoretical weight: 6.76 KDa
Source organism: Naja naja
UniProt:
  • Canonical: A0A0U4N5W4 (Residues: 13-72; Coverage: 83%)
Gene name: CTX13
Sequence domains: u-PAR/Ly-6 domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P6422
Unit cell:
a: 109.331Å b: 109.331Å c: 135.77Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.2 0.199 0.228

Quick links

Citations

1 review citation

Fifty Years of Animal Toxin Research at the Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS.
Tsetlin et al. (2023)
2 other articles

2 mentions without citation

Current Insights in the Mechanisms of Cobra Venom Cytotoxins and Their Complexes in Inducing Toxicity: Implications in Antivenom Therapy.
Kalita et al. (2022)
1 more