Function and Biology Details
Reaction catalysed:
Catalyzes the rearrangement of -S-S- bonds in proteins
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
Assembly name:
Tapasin-ERp57 complex (preferred)
PDBe Complex ID:
PDB-CPX-127517 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (7 distinct):
Beta-2-microglobulin
Molecule details ›
Chain: B
Length: 99 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Immunoglobulin C1-set domain
Length: 99 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P61769 (Residues: 21-119; Coverage: 100%)
Sequence domains: Immunoglobulin C1-set domain
Tapasin
Molecule details ›
Chain: T
Length: 428 amino acids
Theoretical weight: 45.76 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Immunoglobulin C1-set domain
Length: 428 amino acids
Theoretical weight: 45.76 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: O15533 (Residues: 21-448; Coverage: 100%)
Sequence domains: Immunoglobulin C1-set domain
Protein disulfide-isomerase A3
Molecule details ›
HLA class I histocompatibility antigen, A alpha chain
Molecule details ›
Chain: M
Length: 341 amino acids
Theoretical weight: 38.36 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains:
Length: 341 amino acids
Theoretical weight: 38.36 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P04439 (Residues: 25-365; Coverage: 100%)
Sequence domains:
Calreticulin
Molecule details ›
Chain: C
Length: 400 amino acids
Theoretical weight: 46.52 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Calreticulin family
Length: 400 amino acids
Theoretical weight: 46.52 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P27797 (Residues: 18-417; Coverage: 100%)
Sequence domains: Calreticulin family
Ligands and Environments
No bound ligands
No modified residues
