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7qqd

X-ray diffraction
2.7Å resolution

Nuclear factor one X - NFIX in P21

Released:
Model geometry
Fit model/data
Entry authors: Lapi M, Chaves-Sanjuan A, Gourlay LJ, Tiberi M, Polentarutti M, Demitri N, Bais G, Nardini M

Function and Biology Details

Structure analysis Details

Assemblies composition:
monomeric
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-121858 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
Macromolecules (3 distinct):
Nuclear factor 1 X-type Chains: A, B
Molecule details ›
Chains: A, B
Length: 167 amino acids
Theoretical weight: 19.58 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14938 (Residues: 14-176; Coverage: 33%)
Gene name: NFIX
Sequence domains:
NFI binding site (forward) Chain: D
Molecule details ›
Chain: D
Length: 15 nucleotides
Theoretical weight: 4.64 KDa
Source organism: synthetic construct
Expression system: Not provided
NFI binding site (reverse) Chain: F

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ELETTRA BEAMLINE 11.2C
Spacegroup: P21
Unit cell:
a: 43.171Å b: 98.358Å c: 61.629Å
α: 90° β: 92.702° γ: 90°
R-values:
R R work R free
0.198 0.195 0.243
Expression systems:
  • Escherichia coli
  • Not provided