› 7r8c

Electron Microscopy
3.7Å resolution

The structure of human ABCG1

Released:
DOI: 10.2210/pdb7r8c/pdb
PDB entry 7r8c coloured by chain, front view.
PDB entry 7r8c coloured by chain, side view.
PDB entry 7r8c coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Molecular basis of cholesterol efflux via ABCG subfamily transporters.
Sun Y, Wang J, Long T, Qi X, Donnelly L, Elghobashi-Meinhardt N, Esparza L, Cohen JC, Xie XS, Hobbs HH, Li X
OpenAccess logo Proc Natl Acad Sci U S A 118 (2021)
PMID: 34404721
Related structures: EMD-24315

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155353 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATP-binding cassette sub-family G member 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 666 amino acids
Theoretical weight: 74.23 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P45844 (Residues: 1-678; Coverage: 98%)
  • Best match: P45844-4 (Residues: 1-666)
Gene names: ABC8, ABCG1, WHT1
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 3.7Å
Relevant EMDB volumes: EMD-24315
Expression system: Homo sapiens

Quick links

Citations

11 review citations

Migrasomes, a new mode of intercellular communication.
Jiang et al. (2023)
10 more

1 mention without citation

Structural basis for abscisic acid efflux mediated by ABCG25 in Arabidopsis thaliana.
Ying et al. (2023)