› 7ra0

X-ray diffraction
1.36Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190602 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Microtubule-associated protein 1 light chain 3 alpha Chain: A
Molecule details ›
Chain: A
Length: 122 amino acids
Theoretical weight: 14.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9H492 (Residues: 1-120; Coverage: 99%)
Gene name: MAP1LC3A
Sequence domains: Autophagy protein Atg8 ubiquitin like

Ligands and Environments

1 bound ligand:
Ligand 2JI 2 x 2JI
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: I41
Unit cell:
a: 93.622Å b: 93.622Å c: 32.843Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.193 0.201
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Emerging degrader technologies engaging lysosomal pathways.
Ding et al. (2022)
1 more