Function and Biology Details
Reactions catalysed:
4 ferrocytochrome c + O(2) + 8 H(+)(Side 1) = 4 ferricytochrome c + 4 H(2)O(Side 2)
2 superoxide + 2 H(+) = O(2) + H(2)O(2)
Quinol + 2 ferricytochrome c(Side 2) = quinone + 2 ferrocytochrome c(Side 2) + 2 H(+)(Side 2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Cytochrome c oxidase subunit I
- Cytochrome c-like domain
- Cytochrome c-like domain superfamily
- Cytochrome c oxidase subunit IV, actinobacteria
- Cytochrome c oxidase subunit III-like
- Rieske [2Fe-2S] iron-sulphur domain
- Rieske [2Fe-2S] iron-sulphur domain superfamily
- Cytochrome c oxidase-like, subunit I superfamily
21 more domains
Structure analysis Details
Assembly composition:
hetero 24-mer (preferred)
PDBe Complex ID:
PDB-CPX-106256 (preferred)
Entry contents:
12 distinct polypeptide molecules
Macromolecules (12 distinct):
LpqE protein
Molecule details ›
Chains: W, c
Length: 159 amino acids
Theoretical weight: 16.41 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
UniProt:
Length: 159 amino acids
Theoretical weight: 16.41 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
UniProt:
- Canonical:
A0R562 (Residues: 24-182; Coverage: 98%)
cytochrome-c oxidase
Molecule details ›
Chains: K, Q
Length: 312 amino acids
Theoretical weight: 35.2 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
UniProt:
Sequence domains: Cytochrome C oxidase subunit II, periplasmic domain
Length: 312 amino acids
Theoretical weight: 35.2 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
UniProt:
- Canonical: A0R057 (Residues: 27-338; Coverage: 92%)
Sequence domains: Cytochrome C oxidase subunit II, periplasmic domain
Probable cytochrome c oxidase subunit 3
Cytochrome c oxidase polypeptide 4
Cytochrome c oxidase subunit CtaJ
Uncharacterized protein MSMEG_4692/MSMEI_4575
Transmembrane protein
Superoxide dismutase [Cu-Zn]
Cytochrome bc1 complex cytochrome c subunit
Cytochrome bc1 complex cytochrome b subunit
Cytochrome bc1 complex Rieske iron-sulfur subunit
