Function and Biology Details
Reaction catalysed:
ADP + phosphate + acetyl-CoA + oxaloacetate = ATP + citrate + CoA
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Succinyl-CoA synthetase-like
- CoA-binding
- Citrate synthase
- Citrate synthase-like, small alpha subdomain
- ATP-citrate lyase/succinyl-CoA ligase, active site
- ATP-citrate lyase/succinyl-CoA ligase, conserved site
- ATP-citrate synthase/succinyl-CoA ligase, C-terminal domain
- Citrate synthase superfamily
5 more domains
Structure analysis Details
Assembly composition:
homo tetramer (preferred)
Assembly name:
ATP-citrate synthase (preferred)
PDBe Complex ID:
PDB-CPX-156801 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATP-citrate synthase
Molecule details ›
Chains: A, B, C, D
Length: 1101 amino acids
Theoretical weight: 120.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 1101 amino acids
Theoretical weight: 120.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P53396 (Residues: 1-1101; Coverage: 100%)
Sequence domains:
