› 7rmf

Electron Microscopy
7.3Å resolution

Substrate-bound Ura7 filament at low pH

Released:
DOI: 10.2210/pdb7rmf/pdb
PDB entry 7rmf coloured by chain, front view.
PDB entry 7rmf coloured by chain, side view.
PDB entry 7rmf coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation.
Hansen JM, Horowitz A, Lynch EM, Farrell DP, Quispe J, DiMaio F, Kollman JM
OpenAccess logo Elife 10 (2021)
PMID: 34734801
Related structures: EMD-24566

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-247724 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CTP synthase Chains: A, B, C, D, E, F, G, H, I, J, K, W
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, W
Length: 553 amino acids
Theoretical weight: 61.88 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 7.3Å
Relevant EMDB volumes: EMD-24566
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Greater than the sum of parts: Mechanisms of metabolic regulation by enzyme filaments.
Hvorecny et al. (2023)
2 more

1 mention without citation

Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation.
Hansen et al. (2021)