› 7rr5

Electron Microscopy
3.23Å resolution

Structure of ribosomal complex bound with Rbg1/Tma46

Released:
DOI: 10.2210/pdb7rr5/pdb
PDB entry 7rr5 coloured by chain, front view.
PDB entry 7rr5 coloured by chain, side view.
PDB entry 7rr5 coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells.
Zeng F, Li X, Pires-Alves M, Chen X, Hawk CW, Jin H
Cell Rep 37 109877 (2021)
PMID: 34706231
Related structures: EMD-24652

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero 87-mer (preferred)
PDBe Complex ID:
PDB-CPX-103550 (preferred)
Entry contents:
80 distinct polypeptide molecules
7 distinct RNA molecules
Macromolecules (87 distinct):
60S ribosomal protein L2-B Chain: LA
Molecule details ›
Chain: LA
Length: 254 amino acids
Theoretical weight: 27.46 KDa
Source organism: Saccharomyces cerevisiae
Large ribosomal subunit protein uL3 Chain: LB
Molecule details ›
Chain: LB
Length: 387 amino acids
Theoretical weight: 43.85 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: A0A6A5Q627 (Residues: 1-387; Coverage: 100%)
Gene names: GI527_G0005436, RPL3
Sequence domains: Ribosomal protein L3
Large ribosomal subunit protein uL4 C-terminal domain-containing protein Chain: LC
Molecule details ›
Chain: LC
Length: 362 amino acids
Theoretical weight: 39.16 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: A0A6A5Q3W0 (Residues: 1-362; Coverage: 100%)
Gene names: GI527_G0000234, RPL4A
Sequence domains:
Large ribosomal subunit protein uL18 C-terminal eukaryotes domain-containing protein Chain: LD
Molecule details ›
Chain: LD
Length: 297 amino acids
Theoretical weight: 33.76 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: A0A6A5Q0W8 (Residues: 1-297; Coverage: 100%)
Gene names: GI527_G0005918, RPL5
Sequence domains:
60S ribosomal protein L6 Chain: LE
Molecule details ›
Chain: LE
Length: 176 amino acids
Theoretical weight: 20.02 KDa
Source organism: Saccharomyces cerevisiae
60S ribosomal protein L7-A Chain: LF
Molecule details ›
Chain: LF
Length: 244 amino acids
Theoretical weight: 27.69 KDa
Source organism: Saccharomyces cerevisiae
Large ribosomal subunit protein eL8A Chain: LG
Molecule details ›
Chain: LG
Length: 256 amino acids
Theoretical weight: 28.18 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P17076 (Residues: 1-256; Coverage: 100%)
Gene names: MAK7, RPL4A, RPL8A, YHL033C
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Large ribosomal subunit protein uL6A Chain: LH
Molecule details ›
Chain: LH
Length: 191 amino acids
Theoretical weight: 21.61 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05738 (Residues: 1-191; Coverage: 100%)
Gene names: RPL8A, RPL9, RPL9A, YGL147C
Sequence domains: Ribosomal protein L6
RPL10 isoform 1 Chain: LI
Molecule details ›
Chain: LI
Length: 221 amino acids
Theoretical weight: 25.41 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: A0A6A5PUZ5 (Residues: 1-221; Coverage: 100%)
Gene names: GI527_G0003892, RPL10
Sequence domains: Ribosomal protein L16p/L10e
RPL11B isoform 1 Chain: LJ
Molecule details ›
Chain: LJ
Length: 174 amino acids
Theoretical weight: 19.79 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: A0A6A5PYM2 (Residues: 1-174; Coverage: 100%)
Gene names: GI527_G0002509, RPL11B
Sequence domains:
60S ribosomal protein L13 Chain: LL
Molecule details ›
Chain: LL
Length: 199 amino acids
Theoretical weight: 22.6 KDa
Source organism: Saccharomyces cerevisiae
Large ribosomal subunit protein eL14A Chain: LM
Molecule details ›
Chain: LM
Length: 138 amino acids
Theoretical weight: 15.2 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P36105 (Residues: 1-138; Coverage: 100%)
Gene names: RPL14A, YKL006W, YKL153
Sequence domains:
Large ribosomal subunit protein eL15A Chain: LN
Molecule details ›
Chain: LN
Length: 204 amino acids
Theoretical weight: 24.48 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05748 (Residues: 1-204; Coverage: 100%)
Gene names: RPL10A, RPL13A, RPL15A, YL10A, YLR029C
Sequence domains: Ribosomal L15
60S ribosomal protein L16-A Chain: LO
Molecule details ›
Chain: LO
Length: 199 amino acids
Theoretical weight: 22.25 KDa
Source organism: Saccharomyces cerevisiae
60S ribosomal protein L17-A Chain: LP
Molecule details ›
Chain: LP
Length: 184 amino acids
Theoretical weight: 20.59 KDa
Source organism: Saccharomyces cerevisiae
60S ribosomal protein L18-B Chain: LQ
Molecule details ›
Chain: LQ
Length: 186 amino acids
Theoretical weight: 20.61 KDa
Source organism: Saccharomyces cerevisiae
Large ribosomal subunit protein eL19A Chain: LR
Molecule details ›
Chain: LR
Length: 189 amino acids
Theoretical weight: 21.76 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX82 (Residues: 1-189; Coverage: 100%)
Gene names: RPL19A, RPL23A, YBR084BC, YBR084C-A, YL14A
Sequence domains: Ribosomal protein L19e
Large ribosomal subunit protein eL20A Chain: LS
Molecule details ›
Chain: LS
Length: 172 amino acids
Theoretical weight: 20.48 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX23 (Residues: 1-172; Coverage: 100%)
Gene names: RPL18A, RPL18A2, RPL20A, YM9408.04C, YMR242C
Sequence domains: Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
60S ribosomal protein L21-A Chain: LT
Molecule details ›
Chain: LT
Length: 160 amino acids
Theoretical weight: 18.28 KDa
Source organism: Saccharomyces cerevisiae
60S ribosomal protein L22-A Chain: LU
Molecule details ›
Chain: LU
Length: 121 amino acids
Theoretical weight: 13.71 KDa
Source organism: Saccharomyces cerevisiae
60S ribosomal protein L23-B Chain: LV
Molecule details ›
Chain: LV
Length: 137 amino acids
Theoretical weight: 14.49 KDa
Source organism: Saccharomyces cerevisiae
RPL24A isoform 1 Chain: LW
Molecule details ›
Chain: LW
Length: 155 amino acids
Theoretical weight: 17.66 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: A0A6A5PY83 (Residues: 1-155; Coverage: 100%)
Gene names: GI527_G0002390, RPL24A
Sequence domains: Ribosomal protein L24e
60S ribosomal protein L25 Chain: LX
Molecule details ›
Chain: LX
Length: 142 amino acids
Theoretical weight: 15.79 KDa
Source organism: Saccharomyces cerevisiae
Large ribosomal subunit protein uL24A Chain: LY
Molecule details ›
Chain: LY
Length: 127 amino acids
Theoretical weight: 14.27 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05743 (Residues: 1-127; Coverage: 100%)
Gene names: L8300.4, RPL26, RPL26A, RPL33A, YLR344W
Sequence domains:
60S ribosomal protein L27 Chain: LZ
Molecule details ›
Chain: LZ
Length: 136 amino acids
Theoretical weight: 15.57 KDa
Source organism: Saccharomyces cerevisiae
60S ribosomal protein L28 Chain: La
Molecule details ›
Chain: La
Length: 149 amino acids
Theoretical weight: 16.76 KDa
Source organism: Saccharomyces cerevisiae
60S ribosomal protein L29 Chain: Lb
Molecule details ›
Chain: Lb
Length: 59 amino acids
Theoretical weight: 6.69 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: A0A6A5PWR1 (Residues: 1-59; Coverage: 100%)
Gene names: GI527_G0002126, RPL29
Sequence domains: Ribosomal L29e protein family
Large ribosomal subunit protein eL30 Chain: Lc
Molecule details ›
Chain: Lc
Length: 105 amino acids
Theoretical weight: 11.43 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P14120 (Residues: 1-105; Coverage: 100%)
Gene names: RPL30, RPL32, YGL030W
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
60S ribosomal protein L31-A Chain: Ld
Molecule details ›
Chain: Ld
Length: 113 amino acids
Theoretical weight: 12.98 KDa
Source organism: Saccharomyces cerevisiae
RPL32 isoform 1 Chain: Le
Molecule details ›
Chain: Le
Length: 130 amino acids
Theoretical weight: 14.81 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: A0A6A5Q1M9 (Residues: 1-130; Coverage: 100%)
Gene names: GI527_G0000109, RPL32
Sequence domains: Ribosomal protein L32
60S ribosomal protein L33-A Chain: Lf
Molecule details ›
Chain: Lf
Length: 107 amino acids
Theoretical weight: 12.18 KDa
Source organism: Saccharomyces cerevisiae
60S ribosomal protein L34-A Chain: Lg
Molecule details ›
Chain: Lg
Length: 121 amino acids
Theoretical weight: 13.67 KDa
Source organism: Saccharomyces cerevisiae
60S ribosomal protein L35-A Chain: Lh
Molecule details ›
Chain: Lh
Length: 120 amino acids
Theoretical weight: 13.94 KDa
Source organism: Saccharomyces cerevisiae
Large ribosomal subunit protein eL36A Chain: Li
Molecule details ›
Chain: Li
Length: 100 amino acids
Theoretical weight: 11.15 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05745 (Residues: 1-100; Coverage: 100%)
Gene names: RPL36A, RPL39A, YM9646.06, YMR194W
Sequence domains: Ribosomal protein L36e
Ribosomal protein L37 Chain: Lj
Molecule details ›
Chain: Lj
Length: 88 amino acids
Theoretical weight: 9.88 KDa
Source organism: Saccharomyces cerevisiae
RPL38 isoform 1 Chain: Lk
Molecule details ›
Chain: Lk
Length: 78 amino acids
Theoretical weight: 8.85 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: A0A6A5PUL8 (Residues: 1-78; Coverage: 100%)
Gene names: GI527_G0004139, RPL38
Sequence domains: Ribosomal L38e protein family
60S ribosomal protein L39 Chain: Ll
Molecule details ›
Chain: Ll
Length: 51 amino acids
Theoretical weight: 6.36 KDa
Source organism: Saccharomyces cerevisiae
Ubiquitin-60S ribosomal protein L40 Chain: Lm
Molecule details ›
Chain: Lm
Length: 128 amino acids
Theoretical weight: 14.58 KDa
Source organism: Saccharomyces cerevisiae
Small ribosomal subunit protein eS32A Chain: Ln
Molecule details ›
Chain: Ln
Length: 25 amino acids
Theoretical weight: 3.35 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX86 (Residues: 1-25; Coverage: 100%)
Gene names: D1290, RPL41A, RPL47A, YDL184C, YL41A
Sequence domains: Ribosomal protein L41
60S ribosomal protein L42-A Chain: Lo
Molecule details ›
Chain: Lo
Length: 106 amino acids
Theoretical weight: 12.25 KDa
Source organism: Saccharomyces cerevisiae
Large ribosomal subunit protein eL43A Chain: Lp
Molecule details ›
Chain: Lp
Length: 92 amino acids
Theoretical weight: 10.11 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0CX25 (Residues: 1-92; Coverage: 100%)
Gene names: RPL43A, YP9499.02, YPR043W
Sequence domains: Ribosomal L37ae protein family
RPP0 isoform 1 Chain: P0
Molecule details ›
Chain: P0
Length: 312 amino acids
Theoretical weight: 33.75 KDa
Source organism: Saccharomyces cerevisiae
RPL12A isoform 1 Chain: P2
Molecule details ›
Chain: P2
Length: 165 amino acids
Theoretical weight: 17.85 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: A0A6A5Q275 (Residues: 1-165; Coverage: 100%)
Gene names: GI527_G0001353, GI527_G0001724, RPL12A, RPL12B
Sequence domains:
40S ribosomal protein S0 Chain: SA
Molecule details ›
Chain: SA
Length: 252 amino acids
Theoretical weight: 28.05 KDa
Source organism: Saccharomyces cerevisiae
Small ribosomal subunit protein eS1 Chain: SB
Molecule details ›
Chain: SB
Length: 255 amino acids
Theoretical weight: 28.8 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: A0A6A5PRY4 (Residues: 1-255; Coverage: 100%)
Gene names: GI527_G0004262, RPS1, RPS1A
Sequence domains: Ribosomal S3Ae family
S5 DRBM domain-containing protein Chain: SC
Molecule details ›
Chain: SC
Length: 254 amino acids
Theoretical weight: 27.49 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: A0A6A5PWF7 (Residues: 1-254; Coverage: 100%)
Gene names: GI527_G0002294, RPS2
Sequence domains:
40S ribosomal protein S3 Chain: SD
Molecule details ›
Chain: SD
Length: 240 amino acids
Theoretical weight: 26.54 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: A0A6A5Q3Q1 (Residues: 1-240; Coverage: 100%)
Gene names: GI527_G0004928, RPS3
Sequence domains:
40S ribosomal protein S4 Chain: SE
Molecule details ›
Chain: SE
Length: 261 amino acids
Theoretical weight: 29.47 KDa
Source organism: Saccharomyces cerevisiae
Small ribosomal subunit protein uS7 domain-containing protein Chain: SF
Molecule details ›
Chain: SF
Length: 225 amino acids
Theoretical weight: 25.07 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: A0A1L4AA68 (Residues: 1-225; Coverage: 100%)
Gene names: GI527_G0003379, RPS5
Sequence domains: Ribosomal protein S7p/S5e
40S ribosomal protein S6 Chain: SG
Molecule details ›
Chain: SG
Length: 236 amino acids
Theoretical weight: 27.05 KDa
Source organism: Saccharomyces cerevisiae
40S ribosomal protein S7 Chain: SH
Molecule details ›
Chain: SH
Length: 190 amino acids
Theoretical weight: 21.66 KDa
Source organism: Saccharomyces cerevisiae
40S ribosomal protein S8 Chain: SI
Molecule details ›
Chain: SI
Length: 200 amino acids
Theoretical weight: 22.54 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: A0A6A5Q1H1 (Residues: 1-200; Coverage: 100%)
Gene names: GI527_G0000128, GI527_G0001909, RPS8A, RPS8B
Sequence domains: Ribosomal protein S8e
40S ribosomal protein S9-A Chain: SJ
Molecule details ›
Chain: SJ
Length: 197 amino acids
Theoretical weight: 22.49 KDa
Source organism: Saccharomyces cerevisiae
40S ribosomal protein S10-A Chain: SK
Molecule details ›
Chain: SK
Length: 105 amino acids
Theoretical weight: 12.76 KDa
Source organism: Saccharomyces cerevisiae
40S ribosomal protein S11-B Chain: SL
Molecule details ›
Chain: SL
Length: 156 amino acids
Theoretical weight: 17.79 KDa
Source organism: Saccharomyces cerevisiae
40S ribosomal protein S12 Chain: SM
Molecule details ›
Chain: SM
Length: 143 amino acids
Theoretical weight: 15.49 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: A0A6A5Q8I3 (Residues: 1-143; Coverage: 100%)
Gene names: GI527_G0005738, RPS12
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
40S ribosomal protein S13 Chain: SN
Molecule details ›
Chain: SN
Length: 151 amino acids
Theoretical weight: 17.06 KDa
Source organism: Saccharomyces cerevisiae
40S ribosomal protein S14-B Chain: SO
Molecule details ›
Chain: SO
Length: 138 amino acids
Theoretical weight: 14.68 KDa
Source organism: Saccharomyces cerevisiae
RPS15 isoform 1 Chain: SP
Molecule details ›
Chain: SP
Length: 142 amino acids
Theoretical weight: 16.03 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: A0A6A5Q6F2 (Residues: 1-142; Coverage: 100%)
Gene names: GI527_G0005323, RPS15
Sequence domains: Ribosomal protein S19
40S ribosomal protein S16-A Chain: SQ
Molecule details ›
Chain: SQ
Length: 143 amino acids
Theoretical weight: 15.88 KDa
Source organism: Saccharomyces cerevisiae
40S ribosomal protein S17-A Chain: SR
Molecule details ›
Chain: SR
Length: 136 amino acids
Theoretical weight: 15.82 KDa
Source organism: Saccharomyces cerevisiae
40S ribosomal protein S18-B Chain: SS
Molecule details ›
Chain: SS
Length: 146 amino acids
Theoretical weight: 17.07 KDa
Source organism: Saccharomyces cerevisiae
40S ribosomal protein S19-A Chain: ST
Molecule details ›
Chain: ST
Length: 144 amino acids
Theoretical weight: 15.94 KDa
Source organism: Saccharomyces cerevisiae
Small ribosomal subunit protein uS10 domain-containing protein Chain: SU
Molecule details ›
Chain: SU
Length: 121 amino acids
Theoretical weight: 13.93 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: A0A6A5PVE9 (Residues: 1-121; Coverage: 100%)
Gene names: GI527_G0002766, RPS20
Sequence domains: Ribosomal protein S10p/S20e
Small ribosomal subunit protein eS21A Chain: SV
Molecule details ›
Chain: SV
Length: 87 amino acids
Theoretical weight: 9.76 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0C0V8 (Residues: 1-87; Coverage: 100%)
Gene names: RPS21A, RPS25, RPS25A, RPS26A, YKR057W
Sequence domains: Ribosomal protein S21e
RPS22A isoform 1 Chain: SW
Molecule details ›
Chain: SW
Length: 130 amino acids
Theoretical weight: 14.65 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: A0A6A5PSE9 (Residues: 1-130; Coverage: 100%)
Gene names: GI527_G0003062, RPS22A
Sequence domains: Ribosomal protein S8
40S ribosomal protein S23 Chain: SX
Molecule details ›
Chain: SX
Length: 145 amino acids
Theoretical weight: 16.07 KDa
Source organism: Saccharomyces cerevisiae
40S ribosomal protein S24 Chain: SY
Molecule details ›
Chain: SY
Length: 135 amino acids
Theoretical weight: 15.36 KDa
Source organism: Saccharomyces cerevisiae
40S ribosomal protein S25 Chain: SZ
Molecule details ›
Chain: SZ
Length: 108 amino acids
Theoretical weight: 12.07 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: A0A6A5PZ18 (Residues: 1-108; Coverage: 100%)
Gene names: GI527_G0002448, RPS25A
Sequence domains: S25 ribosomal protein
40S ribosomal protein S26 Chain: Sa
Molecule details ›
Chain: Sa
Length: 119 amino acids
Theoretical weight: 13.48 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: A0A6A5Q0E8 (Residues: 1-119; Coverage: 100%)
Gene names: GI527_G0001937, RPS26B
Sequence domains: Ribosomal protein S26e
Small ribosomal subunit protein eS27A Chain: Sb
Molecule details ›
Chain: Sb
Length: 82 amino acids
Theoretical weight: 8.89 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P35997 (Residues: 1-82; Coverage: 100%)
Gene names: RPS27A, YKL156W
Sequence domains: Ribosomal protein S27
RPS28A isoform 1 Chain: Sc
Molecule details ›
Chain: Sc
Length: 67 amino acids
Theoretical weight: 7.61 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: A0A6A5Q700 (Residues: 1-67; Coverage: 100%)
Gene names: GI527_G0005539, RPS28A
Sequence domains: Ribosomal protein S28e
RPS29A isoform 1 Chain: Sd
Molecule details ›
Chain: Sd
Length: 56 amino acids
Theoretical weight: 6.68 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: A0A6A5PV92 (Residues: 1-56; Coverage: 100%)
Gene names: GI527_G0004207, RPS29A
Sequence domains: Ribosomal protein S14p/S29e
40S ribosomal protein S30 Chain: Se
Molecule details ›
Chain: Se
Length: 63 amino acids
Theoretical weight: 7.14 KDa
Source organism: Saccharomyces cerevisiae
RPS31 isoform 1 Chain: Sf
Molecule details ›
Chain: Sf
Length: 152 amino acids
Theoretical weight: 17.25 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: A0A6A5PU37 (Residues: 1-152; Coverage: 100%)
Gene names: GI527_G0003985, RPS31
Sequence domains:
Guanine nucleotide-binding protein subunit beta-like protein Chain: Sg
Molecule details ›
Chain: Sg
Length: 319 amino acids
Theoretical weight: 34.84 KDa
Source organism: Saccharomyces cerevisiae
Eukaryotic translation initiation factor 5A Chain: 5
Molecule details ›
Chain: 5
Length: 157 amino acids
Theoretical weight: 17.22 KDa
Source organism: Saccharomyces cerevisiae
RBG1 isoform 1 Chain: R
Molecule details ›
Chain: R
Length: 410 amino acids
Theoretical weight: 45.47 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: A0A6A5PWT7 (Residues: 1-369; Coverage: 100%)
Gene names: GI527_G0000029, RBG1
Sequence domains:
C3H1-type domain-containing protein Chain: T
Molecule details ›
Chain: T
Length: 345 amino acids
Theoretical weight: 39.59 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: A0A6A5Q867 (Residues: 1-345; Coverage: 100%)
Gene names: GI527_G0005465, TMA46
Sequence domains: DRG Family Regulatory Proteins, Tma46
60S ribosomal protein L1 Chain: L1
Molecule details ›
Chain: L1
Length: 210 amino acids
Theoretical weight: 17.89 KDa
Source organism: Saccharomyces cerevisiae
25S ribosomal RNA Chain: C1
Molecule details ›
Chain: C1
Length: 3396 nucleotides
Theoretical weight: 1097.49 KDa
Sequence domains: Eukaryotic large subunit ribosomal RNA
5S ribosomal RNA Chain: C4
Molecule details ›
Chain: C4
Length: 121 nucleotides
Theoretical weight: 38.95 KDa
Sequence domains: 5S ribosomal RNA
5.8S ribosomal RNA Chain: C3
Molecule details ›
Chain: C3
Length: 158 nucleotides
Theoretical weight: 50.68 KDa
Sequence domains: 5.8S ribosomal RNA
18S Ribosomal RNA Chain: C2
Molecule details ›
Chain: C2
Length: 1800 nucleotides
Theoretical weight: 579.76 KDa
Sequence domains: Eukaryotic small subunit ribosomal RNA
A-tRNA Chain: A
Molecule details ›
Chain: A
Length: 76 nucleotides
Theoretical weight: 24.36 KDa
Sequence domains: tRNA
P-tRNA Chain: P
Molecule details ›
Chain: P
Length: 76 nucleotides
Theoretical weight: 24.45 KDa
Sequence domains: tRNA
Messenger RNA Chain: m
Molecule details ›
Chain: m
Length: 16 nucleotides
Theoretical weight: 5.23 KDa

Ligands and Environments

3 bound ligands:
Ligand MG 286 x MG
Ligand ASP 1 x ASP
Ligand ZN 8 x ZN
1 modified residue:
Ligand 5CT 1 x 5CT

Experiments and Validation Details

Entry percentile scores
Resolution: 3.23Å
Relevant EMDB volumes: EMD-24652
Expression system: Saccharomyces cerevisiae

Quick links

Citations

1 review citation

Developmentally regulated GTPases: structure, function and roles in disease.
Westrip et al. (2021)
4 other articles

2 mentions without citation

Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells.
Zeng et al. (2021)
1 more