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7smq

Electron Microscopy
2.74Å resolution

Cryo-EM structure of Torpedo acetylcholine receptor in apo form with added cholesterol

Released:
Source organism: Tetronarce californica
Related structures: EMD-25205

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-136090 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (8 distinct):
Acetylcholine receptor subunit alpha Chains: A, D
Molecule details ›
Chains: A, D
Length: 437 amino acids
Theoretical weight: 50.17 KDa
Source organism: Tetronarce californica
UniProt:
  • Canonical: P02710 (Residues: 25-461; Coverage: 100%)
Gene name: CHRNA1
Sequence domains:
Acetylcholine receptor subunit delta Chain: B
Molecule details ›
Chain: B
Length: 501 amino acids
Theoretical weight: 57.63 KDa
Source organism: Tetronarce californica
UniProt:
  • Canonical: P02718 (Residues: 22-522; Coverage: 100%)
Gene name: chrnd
Sequence domains:
Acetylcholine receptor subunit beta Chain: C
Acetylcholine receptor subunit gamma Chain: E

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 2.74Å
Relevant EMDB volumes: EMD-25205