› 7t2a

X-ray diffraction
3.04Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-137851 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
HLA class II histocompatibility antigen, DP alpha 1 chain Chains: A, D
Molecule details ›
Chains: A, D
Length: 181 amino acids
Theoretical weight: 20.94 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P20036 (Residues: 32-212; Coverage: 78%)
Gene names: HLA-DP1A, HLA-DPA1, HLASB
Sequence domains:
HLA class II histocompatibility antigen, DP beta 1 chain Chains: B, E
Molecule details ›
Chains: B, E
Length: 188 amino acids
Theoretical weight: 21.92 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P04440 (Residues: 30-217; Coverage: 82%)
Gene names: HLA-DP1B, HLA-DPB1
Sequence domains:
Pneumolysin Chains: C, F
Molecule details ›
Chains: C, F
Length: 15 amino acids
Theoretical weight: 1.83 KDa
Source organism: Streptococcus pneumoniae
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q04IN8 (Residues: 429-441; Coverage: 3%)
Gene names: SPD_1726, ply

Ligands and Environments

1 bound ligand:
Ligand NAG 4 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Spacegroup: P41212
Unit cell:
a: 101.669Å b: 101.669Å c: 215.187Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.219 0.217 0.259
Expression system: Trichoplusia ni

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