› 7tkw

X-ray diffraction
1.85Å resolution

Crystal structure of R14A human Galectin-7 mutant

Released:
DOI: 10.2210/pdb7tkw/pdb
Model geometry
Fit model/data
PDB entry 7tkw coloured by chain, front view.
PDB entry 7tkw coloured by chain, side view.
PDB entry 7tkw coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Pham NTH, Calmettes C, Doucet N

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155680 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Galectin-7 Chains: A, B
Molecule details ›
Chains: A, B
Length: 135 amino acids
Theoretical weight: 14.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P47929 (Residues: 2-136; Coverage: 99%)
Gene names: LGALS7, LGALS7B, PIG1
Sequence domains: Galactoside-binding lectin

Ligands and Environments

2 bound ligands:
Ligand GOL 4 x GOL
Ligand PEG 2 x PEG
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P212121
Unit cell:
a: 53.75Å b: 64.95Å c: 70.41Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.195 0.193 0.231
Expression system: Escherichia coli BL21(DE3)

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