Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Immunoglobulin C1-set
- MHC class I alpha chain, alpha1 alpha2 domains
- Beta-2-Microglobulin
- Immunoglobulin/major histocompatibility complex, conserved site
- Immunoglobulin-like domain
- Immunoglobulin-like domain superfamily
- Immunoglobulin-like fold
- MHC classes I/II-like antigen recognition protein
2 more domains
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-112696 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Ig-like domain-containing protein
Molecule details ›
Chain: A
Length: 274 amino acids
Theoretical weight: 31.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 274 amino acids
Theoretical weight: 31.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
D5H3J5 (Residues: 25-298; Coverage: 81%)
Sequence domains:
Beta-2-microglobulin
Molecule details ›
Chain: B
Length: 100 amino acids
Theoretical weight: 11.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Immunoglobulin C1-set domain
Length: 100 amino acids
Theoretical weight: 11.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Sequence domains: Immunoglobulin C1-set domain
MHC class II alpha chain N-terminal domain-containing protein
Molecule details ›
Chain: P
Length: 9 amino acids
Theoretical weight: 1.09 KDa
Source organism: synthetic construct
Expression system: synthetic construct
UniProt:
Length: 9 amino acids
Theoretical weight: 1.09 KDa
Source organism: synthetic construct
Expression system: synthetic construct
UniProt:
- Canonical: Q9TQB0 (Residues: 36-44; Coverage: 12%)
