7ukh

Electron Microscopy
2.33Å resolution

Human Kv4.2-KChIP2-DPP6 channel complex in an open state, intracellular region

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
PDBe Complex ID:
PDB-CPX-192581 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Potassium voltage-gated channel subfamily D member 2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 524 amino acids
Theoretical weight: 59.05 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9NZV8 (Residues: 1-524; Coverage: 83%)
Gene names: KCND2, KIAA1044
Sequence domains:
Kv channel-interacting protein 2 Chains: I, J, K, L
Molecule details ›
Chains: I, J, K, L
Length: 252 amino acids
Theoretical weight: 28.98 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9NS61 (Residues: 1-270; Coverage: 93%)
Gene names: KCHIP2, KCNIP2
Sequence domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.33Å
Relevant EMDB volumes: EMD-26581
Expression system: Homo sapiens