› 7up2

X-ray diffraction
1.13Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194976 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
beta-lactamase Chain: A
Molecule details ›
Chain: A
Length: 246 amino acids
Theoretical weight: 26.01 KDa
Source organism: Pseudomonas aeruginosa
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9XAY4 (Residues: 27-266; Coverage: 98%)
Gene names: CAZ10_38240, CAZ10_38245, blaVIM, blaVIM-1
Sequence domains: Metallo-beta-lactamase superfamily

Ligands and Environments

2 bound ligands:
Ligand ZN 2 x ZN
Ligand NZR 1 x NZR
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P21
Unit cell:
a: 39.56Å b: 67.42Å c: 40.18Å
α: 90° β: 91.67° γ: 90°
R-values:
R R work R free
0.162 0.162 0.173
Expression system: Escherichia coli

Quick links

Citations

1 citations in other articles

α-Aminophosphonate inhibitors of metallo-β-lactamases NDM-1 and VIM-2.
Palica et al. (2023)