› 7utr

Electron Microscopy
3.7Å resolution

CPV Affinity Purified Polyclonal Fab B Site Fab

Released:
DOI: 10.2210/pdb7utr/pdb
PDB entry 7utr coloured by chain, front view.
PDB entry 7utr coloured by chain, side view.
PDB entry 7utr coloured by chain, top view.
Source organisms:
Primary publication:
Cryo EM structures map a post vaccination polyclonal antibody response to canine parvovirus.
Hartmann SR, Charnesky AJ, Früh SP, López-Astacio RA, Weichert WS, DiNunno N, Cho SH, Bator CM, Parrish CR, Hafenstein SL
OpenAccess logo Commun Biol 6 955 (2023)
PMID: 37726539
Related structures: EMD-26787

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
hetero decamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-231146 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Capsid protein VP1 Chains: A, B, C, D, E, F, G, I
Molecule details ›
Chains: A, B, C, D, E, F, G, I
Length: 548 amino acids
Theoretical weight: 61.56 KDa
Source organism: Canine parvovirus strain B
Expression system: Felis catus
UniProt:
  • Canonical: Q11213 (Residues: 180-727; Coverage: 75%)
Sequence domains: Parvovirus coat protein VP2
Light chain antibody fragment Chain: L
Molecule details ›
Chain: L
Length: 95 amino acids
Theoretical weight: 8.1 KDa
Source organism: Canis lupus familiaris
Heavy chain antibody fragment Chain: H

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 3.7Å
Relevant EMDB volumes: EMD-26787
Expression system: Felis catus

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Citations

2 review citations

Current Review of Monoclonal Antibody Therapeutics in Small Animal Medicine.
Wang et al. (2025)
1 more