7uzc

X-ray diffraction
2.2Å resolution

Structure of the SARS-CoV-2 RBD in complex with the mouse antibody Fab fragment, M8a-34

Released:
Model geometry
Fit model/data

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-279666 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (5 distinct):
Spike protein S1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 231 amino acids
Theoretical weight: 25.99 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 328-533; Coverage: 16%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
M8a-34 Fab heavy chain Chains: E, H
Molecule details ›
Chains: E, H
Length: 235 amino acids
Theoretical weight: 25.51 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
M8a-34 Fab light chain Chains: F, L

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: P21
Unit cell:
a: 54.47Å b: 165.165Å c: 93.715Å
α: 90° β: 106.63° γ: 90°
R-values:
R R work R free
0.173 0.172 0.243
Expression system: Homo sapiens