Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Pancreatic trypsin inhibitor Kunitz domain
- Cell wall/choline-binding repeat
- Pancreatic trypsin inhibitor Kunitz domain superfamily
- Proteinase inhibitor I2, Kunitz, conserved site
- CGT/MARTX, cysteine protease (CPD) domain
- Tissue factor pathway inhibitor-like
- TcdA/TcdB toxin, pore forming domain
- CGT/MARTX, cysteine protease (CPD) domain superfamily
4 more domains
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145413 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Toxin B
Molecule details ›
Chain: A
Length: 2375 amino acids
Theoretical weight: 270.45 KDa
Source organism: Clostridioides difficile
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 2375 amino acids
Theoretical weight: 270.45 KDa
Source organism: Clostridioides difficile
Expression system: Escherichia coli
UniProt:
- Canonical:
Q9EXR0 (Residues: 1-2367; Coverage: 100%)
Sequence domains:
Tissue factor pathway inhibitor
Molecule details ›
Chain: K
Length: 251 amino acids
Theoretical weight: 28.68 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Kunitz/Bovine pancreatic trypsin inhibitor domain
Length: 251 amino acids
Theoretical weight: 28.68 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: P10646 (Residues: 1-209; Coverage: 66%)
Sequence domains: Kunitz/Bovine pancreatic trypsin inhibitor domain
