› 7v7b

Electron Microscopy
4.2Å resolution

CryoEM structure of DDB1-VprBP complex in ARM-up conformation

Released:
DOI: 10.2210/pdb7v7b/pdb
PDB entry 7v7b coloured by chain, front view.
PDB entry 7v7b coloured by chain, side view.
PDB entry 7v7b coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Wang D, Xu J, Liu Q, Xiang Y
Related structures: EMD-31765

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172486 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
DDB1- and CUL4-associated factor 1 Chains: A, C
Molecule details ›
Chains: A, C
Length: 1507 amino acids
Theoretical weight: 169.19 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q9Y4B6 (Residues: 1-1507; Coverage: 100%)
Gene names: DCAF1, KIAA0800, RIP, VPRBP
DNA damage-binding protein 1 Chains: B, D
Molecule details ›
Chains: B, D
Length: 1140 amino acids
Theoretical weight: 127.1 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q16531 (Residues: 1-1140; Coverage: 100%)
Gene names: DDB1, XAP1
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.2Å
Relevant EMDB volumes: EMD-31765
Expression system: Trichoplusia ni

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