› 7vaz

X-ray diffraction
2.73Å resolution

Crystal structure of antibody 14A in complex with MUC1 glycopeptide(GlycoS)

Released:
DOI: 10.2210/pdb7vaz/pdb
PDB entry 7vaz coloured by chain, front view.
PDB entry 7vaz coloured by chain, side view.
PDB entry 7vaz coloured by chain, top view.
Source organisms:
Entry authors: Niu J, Xu L, Meng B, Han YB, Yang B

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-225494 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
14A fab light chain Chains: A, C, F
Molecule details ›
Chains: A, C, F
Length: 217 amino acids
Theoretical weight: 23.51 KDa
Source organism: Mus musculus
Expression system: Trichopalpus nigribasis
14A fab heavy chain Chains: B, D, H
Molecule details ›
Chains: B, D, H
Length: 229 amino acids
Theoretical weight: 24.57 KDa
Source organism: Mus musculus
Expression system: Trichopalpus nigribasis
Mucin-1 subunit alpha Chains: E, G, I
Molecule details ›
Chains: E, G, I
Length: 13 amino acids
Theoretical weight: 1.22 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P15941 (Residues: 925-937; Coverage: 1%)
Gene names: MUC1, PUM

Ligands and Environments

1 bound ligand:
Ligand NGA 1 x NGA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P21
Unit cell:
a: 46.558Å b: 226.62Å c: 71.071Å
α: 90° β: 107.69° γ: 90°
R-values:
R R work R free
0.212 0.209 0.264
Expression systems:
  • Trichopalpus nigribasis
  • Not provided

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