› 7ve5

X-ray diffraction
2Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-122224 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
Macromolecules (3 distinct):
Response regulator protein VraR Chains: A, B
Molecule details ›
Chains: A, B
Length: 72 amino acids
Theoretical weight: 8.34 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q2FX09 (Residues: 138-209; Coverage: 34%)
Gene names: SAOUHSC_02098, vraR
Sequence domains: Bacterial regulatory proteins, luxR family
R1-DNA Chain: C
Molecule details ›
Chain: C
Length: 22 nucleotides
Theoretical weight: 6.77 KDa
Source organism: Staphylococcus aureus subsp. aureus Mu50
Expression system: Not provided
R1-DNA Chain: D

Ligands and Environments

1 bound ligand:
Ligand MG 6 x MG
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: NSRRC BEAMLINE TPS 05A
Spacegroup: R3
Unit cell:
a: 60.349Å b: 60.349Å c: 171.521Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.2 0.194 0.255
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

1 citations in other articles

A pH-sensitive switch activates virulence in Salmonella.
Shetty et al. (2023)

1 mention without citation

Structural insights into DNA binding domain of vancomycin-resistance-associated response regulator in complex with its promoter DNA from Staphylococcus aureus.
Kumar et al. (2022)