7wtu

Electron Microscopy
3Å resolution

Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A1 (without CK1)

Released:
Source organism: Homo sapiens
Related structures: EMD-32801

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero 33-mer (preferred)
PDBe Complex ID:
PDB-CPX-129072 (preferred)
Entry contents:
32 distinct polypeptide molecules
1 distinct RNA molecule
Macromolecules (33 distinct):
Small ribosomal subunit protein eS17 Chain: R
Molecule details ›
Chain: R
Length: 135 amino acids
Theoretical weight: 15.58 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P08708 (Residues: 1-135; Coverage: 100%)
Gene names: RPS17, RPS17L
Sequence domains: Ribosomal S17
Small ribosomal subunit protein eS27 Chain: b
Molecule details ›
Chain: b
Length: 84 amino acids
Theoretical weight: 9.48 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P42677 (Residues: 1-84; Coverage: 100%)
Gene names: MPS1, RPS27
Sequence domains: Ribosomal protein S27
Small ribosomal subunit protein eS1 Chain: B
Small ribosomal subunit protein eS28 Chain: c
Small ribosomal subunit protein eS4, X isoform Chain: E
Small ribosomal subunit protein eS30 Chain: e
Small ribosomal subunit protein uS7 Chain: F
Small ribosomal subunit protein eS7 Chain: H
Small ribosomal subunit protein eS6 Chain: G
Small ribosomal subunit protein eS25 Chain: Z
Small ribosomal subunit protein eS24 Chain: Y
RNA-binding protein PNO1 Chain: x
Small ribosomal subunit protein uS12 Chain: X
Bystin Chain: w
Small ribosomal subunit protein uS8 Chain: W
Pre-rRNA-processing protein TSR1 homolog Chain: u
Protein LTV1 homolog Chain: t
Small ribosomal subunit protein eS19 Chain: T
Small ribosomal subunit protein uS13 Chain: S
Small ribosomal subunit protein uS9 Chain: Q
Small ribosomal subunit protein uS19 Chain: P
Small ribosomal subunit protein uS11 Chain: O
Small ribosomal subunit protein uS15 Chain: N
Small ribosomal subunit protein uS17 Chain: L
Small ribosomal subunit protein uS4 Chain: J
Small ribosomal subunit protein eS8 Chain: I
Multifunctional methyltransferase subunit TRM112-like protein Chain: r
18S rRNA (guanine-N(7))-methyltransferase Chain: q
RRP12-like protein Chain: K
Small ribosomal subunit protein eS12 Chain: M
Ubiquitin-ribosomal protein eS31 fusion protein Chain: f
Ribosome biogenesis protein SLX9 homolog Chain: z
18S Ribosomal RNA Chain: 2

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution:
Relevant EMDB volumes: EMD-32801