Function and Biology Details
Reactions catalysed:
L-glutamate 5-semialdehyde + phosphate + NADP(+) = L-glutamyl 5-phosphate + NADPH
ATP + L-glutamate = ADP + L-glutamate 5-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Glutamate/acetylglutamate kinase
- GPR domain
- Acetylglutamate kinase-like superfamily
- Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase
- Delta l-pyrroline-5-carboxylate synthetase
- Gamma-glutamyl phosphate reductase GPR, conserved site
- Aldehyde dehydrogenase, C-terminal
- Aldehyde dehydrogenase, N-terminal
5 more domains
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Delta-1-pyrroline-5-carboxylate synthase (preferred)
PDBe Complex ID:
PDB-CPX-194287 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Delta-1-pyrroline-5-carboxylate synthase
Molecule details ›
Chains: A, B
Length: 776 amino acids
Theoretical weight: 84.2 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
Sequence domains:
Length: 776 amino acids
Theoretical weight: 84.2 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
- Canonical:
Q9VNW6 (Residues: 1-776; Coverage: 100%)
Sequence domains:
