› 7x5c

Solution NMR

Solution structure of Tetrahymena p75OB1-p50PBM

Released:
DOI: 10.2210/pdb7x5c/pdb
PDB entry 7x5c coloured by chain, ensemble of 20 models, front view.
PDB entry 7x5c coloured by chain, ensemble of 20 models, side view.
PDB entry 7x5c coloured by chain, ensemble of 20 models, top view.
Source organism: Tetrahymena
Primary publication:
Association of the CST complex and p50 in Tetrahymena is crucial for telomere maintenance
Ma Y, Tang T, Wu B, Xue H, Cao Y, Wu J, Wan B, Lei M
Structure (2022)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-216550 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Telomerase-associated protein of 75 kDa Chain: A
Molecule details ›
Chain: A
Length: 172 amino acids
Theoretical weight: 20.13 KDa
Source organism: Tetrahymena
Expression system: Escherichia coli
UniProt:
  • Canonical: A0PGB2 (Residues: 1-179; Coverage: 28%)
Gene names: TAP75, TTHERM_00059040
Telomerase-associated protein of 50 kDa Chain: B
Molecule details ›
Chain: B
Length: 14 amino acids
Theoretical weight: 1.54 KDa
Source organism: Tetrahymena
Expression system: Escherichia coli
UniProt:
  • Canonical: D2CVN8 (Residues: 230-243; Coverage: 3%)
Gene names: TAP50, TTHERM_01049190

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 89%
Refinement method: simulated annealing
Expression system: Escherichia coli

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