› 7x8z

Electron Microscopy
4.1Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-279676 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Spike glycoprotein Chain: A
Molecule details ›
Chain: A
Length: 1278 amino acids
Theoretical weight: 141.46 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 1-1208; Coverage: 95%)
Gene names: 2, S
Sequence domains:
Ab188 heavy chain Chain: H
Molecule details ›
Chain: H
Length: 265 amino acids
Theoretical weight: 28.64 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
Ab188 light chain Chain: L

Ligands and Environments

1 bound ligand:
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 4.1Å
Relevant EMDB volumes: EMD-33061
Expression system: Homo sapiens

Quick links

Citations

4 citation in other articles

Overcoming antibody-resistant SARS-CoV-2 variants with bispecific antibodies constructed using non-neutralizing antibodies.
Inoue et al. (2024)
3 more

2 mentions without citation

Potent SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models.
Takeshita et al. (2022)
1 more