Function and Biology Details
Reaction catalysed:
Angiotensin II + H(2)O = angiotensin-(1-7) + L-phenylalanine
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-105830 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Angiotensin-converting enzyme
Molecule details ›
Chains: A, C, E, G
Length: 598 amino acids
Theoretical weight: 69.71 KDa
Source organism: Rhinolophus affinis
Expression system: Escherichia coli
UniProt:
Length: 598 amino acids
Theoretical weight: 69.71 KDa
Source organism: Rhinolophus affinis
Expression system: Escherichia coli
UniProt:
- Canonical:
A0A7D7FA76 (Residues: 18-615; Coverage: 76%)
Spike protein S1
Molecule details ›
Chains: B, D, F, H
Length: 223 amino acids
Theoretical weight: 25.12 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
Length: 223 amino acids
Theoretical weight: 25.12 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
- Canonical: P0DTC2 (Residues: 319-541; Coverage: 18%)
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
