› 7xdh

X-ray diffraction
1.83Å resolution

Crystal structure of a dimeric interlocked parallel G-quadruplex

Released:
DOI: 10.2210/pdb7xdh/pdb
Model geometry
Fit model/data
PDB entry 7xdh coloured by chain, front view.
PDB entry 7xdh coloured by chain, side view.
PDB entry 7xdh coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
Crystal structures of an HIV-1 integrase aptamer: Formation of a water-mediated A•G•G•G•G pentad in an interlocked G-quadruplex.
Ngo KH, Liew CW, Lattmann S, Winnerdy FR, Phan AT
Biochem Biophys Res Commun 613 153-158 (2022)
PMID: 35561583

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-122291 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*GP*GP*GP*GP*TP*GP*GP*GP*AP*GP*GP*AP*GP*GP*GP*T)-3') Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 16 nucleotides
Theoretical weight: 5.14 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand K 10 x K
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P1
Unit cell:
a: 25.685Å b: 30.34Å c: 56.493Å
α: 79.024° β: 83.357° γ: 78.197°
R-values:
R R work R free
0.23 0.227 0.253
Expression system: Not provided

Quick links