› 7xfw

X-ray diffraction
2.07Å resolution

Crystal structure of the ternary complex of Peptidoglycan recognition protein, PGRP-S with hexanoic and tartaric acids at 2.07 A resolution.

Released:
DOI: 10.2210/pdb7xfw/pdb
PDB entry 7xfw coloured by chain, front view.
PDB entry 7xfw coloured by chain, side view.
PDB entry 7xfw coloured by chain, top view.
Source organism: Camelus dromedarius
Primary publication:
Structure of the complex of camel peptidoglycan recognition protein-S with hexanoic acid reveals novel features of the versatile ligand-binding site at the dimeric interface.
Maurya A, Sharma P, Singh PK, Viswanathan V, Kaur P, Sharma S, Singh TP
Biochim Biophys Acta Proteins Proteom 1871 140887 (2022)
PMID: 36596432

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190401 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptidoglycan recognition protein 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 171 amino acids
Theoretical weight: 19.01 KDa
Source organism: Camelus dromedarius
UniProt:
  • Canonical: Q9GK12 (Residues: 23-193; Coverage: 99%)
Gene names: PGLYRP, PGLYRP1, PGRP
Sequence domains: N-acetylmuramoyl-L-alanine amidase

Ligands and Environments

6 bound ligands:
Ligand TLA 3 x TLA
Ligand EDO 6 x EDO
Ligand ACT 3 x ACT
Ligand CL 1 x CL
Ligand 6NA 1 x 6NA
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE MASSIF-1
Spacegroup: I222
Unit cell:
a: 88.889Å b: 101.508Å c: 162.996Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.202 0.2 0.258

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