Function and Biology Details
Reaction catalysed:
Palmitoyl-CoA + L-serine = CoA + 3-dehydro-D-sphinganine + CO(2)
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-220460 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
Serine palmitoyltransferase 2
Molecule details ›
Chain: B
Length: 562 amino acids
Theoretical weight: 63 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Aminotransferase class I and II
Length: 562 amino acids
Theoretical weight: 63 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
O15270 (Residues: 1-562; Coverage: 100%)
Sequence domains: Aminotransferase class I and II
Serine palmitoyltransferase 1
Molecule details ›
Chain: E
Length: 50 amino acids
Theoretical weight: 5.9 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Length: 50 amino acids
Theoretical weight: 5.9 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: O15269 (Residues: 1-50; Coverage: 11%)
ORM1-like protein 3
Serine palmitoyltransferase small subunit A
Serine palmitoyltransferase 1
